I think that I am close to your situation. I have been DX with UC for 3 years, and cannot say that I have had any long term remission that did not involve prednisone. I had better moments than others, but "normal" was very relative. ihave been on Asacol, switched to Lialda, on/off prednisone, and am currently on Imuran and Remicade. The Remicade is new so I am still holding out hope. I have been on/off prednisone since February 07, with my highest dosage being 60 mg. I have finally started my taper and am on 30mg with the schedule showing me to be off by mid November. I have every side effect from the prednisone ecept psychosis. I have some nasty ones involving eye irritation and blurry vision. Now I have some ugly looking infections in my thumb (thank you immuno suppresants). It seems as if the medication is worse than the disease sometimes. However, when my flare is roaring, I beg for the prednisone. If the Remicade does not help get off the prednisonethen I, too, may have to consider surgery. It is not a decision I will take lightly, but at this point the medication (especially the prednisone) is really taking a toll on me.