Prednisone is both a miracle drug and an evil curse at the same time. I took it about
6 years ago and it was wonderful for the first month. It cleared up all my UC symptoms within 3 days and made me feel like Superman. A month later all the usual side effects appeared, acne, moon face, weight gain, insomnia, mood swings and being tired all the time but couldn’t get much sleep. I couldn’t go below 20mg per day without flaring. After 6 months I finally got off it but I had to go back on a month later for 3 months. I then went into a 2 ½ year remission. When my current flair started, May 2005, I was determined not to go back on pred again. I will not use it again unless I have consistently 15 BMs per day or more.
Diagnosed in 2000 at age 43 with UC extending half way across transverse colon.
Allergic reaction to Asacol, Pentasa and Dipentum - can’t take any more 5ASAs.
Prednisone - worked well for 1 month, then side effects became unbearable.
6-MP - blood tests showed not metabolizing properly.
Flagyl, Ciprofloxin, VSL#3, Adacolumn Apheresis – all had no effect
Corticosteroid enemas in both liquid and foam - no effect
Methotrexate with Remicade - 7 infusions with no improvement
Folic Acid and B12 injections.