Doc, I feel exactly that way most of the time! "If its not broken......"
My gastro who I have been seeing since I was 19 (Im 36 now) used to throw out Imuran as "the big bad drug". He would say "If pred doesnt work this time, we'll have to go to Imuran." I was so scared! I was trying to envision drugs WORSE than prednisone. I can tell you all after having colitis since the age of 1, I havent had worse than prednisone. I have had many drugs not work, but nothing compared to the panic attacks and joint pain I lived with. I was expecting to get sick on Imuran, but as you said, the side effects are definitely more on the rare side.
I just had blood tests done (promethius) for the 2nd time, and got my dose pumped up again. Now I am at 150 mg. Its weird to feel healthy, but get your drug dose upped. I trust they know what they are doing!
Donna, how long have you been on Imuran so far? I think it took me several months to really say "WOW..." Getting healthy was in combination with getting 70 mg of prednisone out of my body.
I wish you good luck...I think this drug saved my colon and my sanity.