Colazal and Abdominal Pain

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bamap
Regular Member


Date Joined Jul 2007
Total Posts : 26
   Posted 10/16/2007 7:32 PM (GMT -7)   
Hi all.
I'm on 40mg prednisone and have occasionally tried to lessen the amount of colazal I'm taking (thinking the pred should be enough).  Every time I've done this, I notice abdominal tenderness on the left side of my belly button and a complete loss of appetite (which is very strange on 40mg pred).  I'm not having any other typical UC symptoms.  Could this be from NOT taking the full dose (3/3xday) of colazal consistently?  I'm associating it with this, but maybe it's coming from something else?  It seems when I start taking it again consistenly, appetite comes back and tenderness lessens.  I know what you'll say ... so keep taking it.  I will, but wondered if anyone else has experienced this.
Thanks!

UMDTerp2001
Regular Member


Date Joined Sep 2006
Total Posts : 246
   Posted 10/17/2007 1:03 AM (GMT -7)   
I'm on 4 to 6 colazal a day. Never experienced these effects or any side effects that i know of. Definitely run this past your GI.
 
 
__________________________________________________________________________________
- 29 y/o male living in the DC Metropolitan region
- UC diagnosed - April, 2006 - symptoms came on sudden
- GI could not determine type of UC as I was too inflamed during the colonoscopy
- Completed 3rd Prednisone taper on 4/13/07 - Tapered from early January through mid-April after being hospitalized from a bad flare with anemia & severe joint pain.
- Currently in remission
- 6 Colazal/day, 1 Multivitamin, Fish oil, Primal Defense Probiotics 2/day, Iron supplement when bleeding
- Use small dose (5-10mg) of prednisone occassionally to manage joint pain


Old Hat
Veteran Member


Date Joined Feb 2007
Total Posts : 5135
   Posted 10/17/2007 8:01 AM (GMT -7)   
Do you have pancolitis? What is your doctor's strategy for getting you off Prednisone? Ideally, you should taper off Pred & onto 5-ASA med, such as Colazal. Colazal recently entered Phase 3 (of 4) clinical trials by NIH study participants. When it was 1st prescribed for me in 2003, the recommended dose was 3 X 3 capsules daily-- this was during Phase 2 of NIH clinical trials. I believe that the recommended daily dosage has since been decreased to 6 capsules daily; however, there are members writing to this site who take higher doses for long periods & seem to tolerate Colazal well. I myself cannot take Colazal at 6 or more capsules daily for more than 10 weeks w/o experiencing some u.t. problems, but did well on 1-3 capsules daily during a 20 month-remission period that ended with slight flare this past July. Hope this info helps you; I never had abdominal pain due to UC meds. / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 Colazal daily; seem to have regained remission)

Old Hat
Veteran Member


Date Joined Feb 2007
Total Posts : 5135
   Posted 10/17/2007 8:30 AM (GMT -7)   
P.S. to previous message: do you take your oral meds with food? This is always a good idea to reduce chances for stomach irritation. Also drink plenty of water daily. / Old Hat

bamap
Regular Member


Date Joined Jul 2007
Total Posts : 26
   Posted 10/17/2007 7:36 PM (GMT -7)   
Thanks for all the info. I'm on prednisone for another auto-immune disorder called Churg Strauss. I *think* the Ulcerative Colitis is a result of the CSS (systemic over-inflammation of blood vessels). I've been on Colazal since I was dx with UC in May. I was told it was for maintenance and probably needed to take it indefinitely. I will be on prednisone for a while, unfortunately. The hardest part of all of this is deciphering symptoms from side effects. I'm on a lot of medication. I guess until whatever it is declares itself a little more obviously, I'll wait it out. I haven't lost much weight, so I'll try not to worry! Thanks again.
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