Sulfasalazine possesses antimicrobial properties?

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Regular Member

Date Joined Mar 2007
Total Posts : 157
   Posted 10/18/2007 1:08 PM (GMT -6)   
According to Wikipedia and other sources, sulfasalazine can be classified as an antimicrobial agent. This I find quite interesting given the efficacy of the drug itself in treating ulcerative colitis. I'd be curious to know how many doctors and patients alike have ignored this important mechanism. I wonder if it would be safe to assume the same of mesalazine?

Was anyone else aware of this?

Veteran Member

Date Joined Aug 2007
Total Posts : 2204
   Posted 10/18/2007 1:23 PM (GMT -6)   
Yes, I believe Elaine Gotschall, developer of the Specific Carbohydrate Diet, talks about it's antimicrobial effect, although I can't seem to find the discussion on the SCD Web site at the moment. She felt sulfasalazine (Azulfadine) was the drug of choice for treating UC or Crohn's colitis.
Diagnosed with ulcerative colitis spring 1999
C-scope confirmed UC diagnosis 9/18/2007
No explanation for right side pain and thickening of bowel wall
Maintenance dose sulfasalazine, back on a pred taper for first flare in years
Probiotics, l-glutamine and fish oil caps. George's aloe vera juice and Mucosaheal.

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