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Remicade not working - Humira, Enbrel etc..

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Ulcerative Colitis
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whataboutyouphil
New Member
Joined : Oct 2007
Posts : 4
Posted 10/20/2007 1:10 PM (GMT -8)
I was on Remicade and my body built up an immunity after months of it working great. Docs increased the dosage and frequency with no luck.

Anyone have this happen with Remicade and what did you do? I am hoping that Humira or Enbrel will get approval and be out of trials soon.

I can not get into remission and I am stuck on steriods, which of course I can't stay on for long because of all the bad side effects.

Docs keep talking about surgery.

Anyone?

Thanks!

I just expanded on your post title for more responses.

Post Edited By Moderator (Red_34) : 10/21/2007 6:34:11 AM (GMT-6)

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Red_34
Elite Member
Joined : Apr 2004
Posts : 23581
Posted 10/21/2007 4:38 AM (GMT -8)
Hi there and welcome to Healingwell. I have no advice for you since I'm not to the Remicade option yet. I just wanted say welcome and to bump your thread to the top for others to see.
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gela
Regular Member
Joined : Jun 2005
Posts : 133
Posted 10/21/2007 4:50 AM (GMT -8)
are you in an area that does any research?  my doc does and i know there is a nationwide research study on humira for uc right now or very soon.  there are actually 3-4 studies going on right now.  one is for those that did n't respond specifically to remicade.  check into it.  i have gone into remission only through the studies i have done.  they are very safe to do now a days.

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Beth75
Veteran Member
Joined : Jul 2007
Posts : 2158
Posted 10/21/2007 11:07 AM (GMT -8)
my friends Dad is on the drug trial for Humira right now for UC, unfortunately they think he is on the placebo, it is not helping him though once the 8 weeks is up if he is on the placebo they will start him on the Humira so maybe in the long run it is not unfortunate and it will help him.
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Mamas Boys
Veteran Member
Joined : Oct 2005
Posts : 1460
Posted 10/21/2007 12:22 PM (GMT -8)
Have you every tried Imuran (azathioprine) or 6mp?  My doctor has me on azathioprine together with the Remicade to prevent such an immunity from happening.  Ask your doctor about that.

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jujub
Elite Member
Joined : Mar 2003
Posts : 10424
Posted 10/21/2007 12:28 PM (GMT -8)
My doctor's group is participating in one of the humira tests, and my understanding is that the early results showed it to be no more effective than Remicade overall, and more expensive. However for some people it worked better. 

My doc also recommends Imuran along with Remi to prevent the development of allergic reactions.

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beanie6421
Regular Member
Joined : Feb 2003
Posts : 51
Posted 10/22/2007 7:14 AM (GMT -8)
I did Remicade three or four times, never noticed much, except I received it where patients were being treated for cancer, so it was a great reminder of how much worse I could be.

The last try, I got severe temporary arthritis, and needed a ton of Prednisone to get back to normal, so the doc says I'm considered allergic to it and can't try again.
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