I can't believe so many of us are in the same boat. LWW1993, we are in almost exactly the same position -- I have a 15 month old baby and flared post-pregnancy in a terrible way and I've been trying to get things back under control ever since. We'd really like to have another baby soon, but I want to be healthy first.
This is such a timely topic as I'm actually going to the GI tomorrow morning and 6mp and Remicade are the next steps for me. He feels comfortable with me staying on 6mp should I get pregnant as he tells me that many transplant patients who take much higher doses have delivered many healthy babies while on the drug.
I'm actually more concerned about breastfeeding as I really want to breastfeed a second baby as long as possible - I had to suddenly wean my daughter at 5 months because I was on such high doses of prednisone and it was one of the worst things I've ever had to go through. I've been doing a lot of research on 6mp and pregnancy and breastfeeding. The most recent information I got from Motherisk (a service offered by major Toronto hospitals that provides the most current information on medication and pregnancy and breastfeeding) was that 6mp at low doses was compatible with breastfeeding as long as the baby's development was monitored closely.
It is a very difficult decision to make though and I'm still not sure if I'm comfortable going on 6mp and getting pregnant. I feel slightly more comfortable with Remicade alone; however, I'm not sure if my GI would consider putting me on Remicade alone. Protocol seems to indicate that both drugs should be taken together to increase effectiveness and the likelihood of not developing antibodies. I'm going to ask him tomorrow what he thinks. I can report back if others are interested.
Unfortunately, I don't have much choice at this point as I cannot take prednisone anymore (osteopenia and it makes me so crazy I refuse to be on it again), and I have to take something as the maximum Asacol dosage and Pentasa enemas just aren't working any longer.
It is so awful for so many women to have to make these tough decisions in their childbearing years. It creates so much extra stress that we really don't need. Hopefully as more studies come out reporting on pregnant women who've taken these drugs we can rest a bit easier.
32-yr old female, diagnosed with left-sided UC in 2002, likely now pancolitis
1st severe flare started post-pregnancy in December 2006
4 x 400mg Asacol 3 times a day
Off prednisone finally!
VSL#3, calcium + D, B-100, iron, vegetarian/whole foods diet
Osteopenia (diagnosed May 2007)