I have experienced much more fatigue on the Imuran. I recently started taking it in the evening (because I also have trouble sleeping) but it doesn't seem to do much. I also have occassional headaches that I take Tylenol for. Not sure if they are from the Imuran or not. I also take Tylenol PM once in a while to help me fall asleep.
The bruising would be worth checking out with your doctor. Though not likely, that could be a sign of something more serious.
Dx Left-sided UC Dec. 2006
Azathioprine (Imuran) 125mg/day
Prednisone 5mg/day (trying to taper-started at 60 6/1)
Multivitamin, B complex vit., fish oil, calcium, fiber supplement, probiotic