Prednisolone and Imuran?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

New Member

Date Joined Oct 2007
Total Posts : 1
   Posted 10/28/2007 2:54 PM (GMT -6)   
Hi there, First I love these forums they've helped me so much! I'm quite the lurker but now I have a problem...
I'm a little bit worried about the amount of medication I'm on, Specifically Imuran and Prednisolone at the same time! Is being on those two common?
Do you think I'm on too much medication?

Thanks in advance.....I'm sure I'm just being a worry-bug!
20 years old- Ulcerative Colitis
Diagnosed at age 15
((Prednisolone- 15 mg, Imuran (Azathiprine)- 200 mg, Codeine Phosphate- 90mg, Ferrous sulphate- 600mg, Colazide- 3000mg)

Regular Member

Date Joined Aug 2007
Total Posts : 97
   Posted 10/28/2007 5:38 PM (GMT -6)   

Hello Mypoeticsin..... First, welcome to the site.  Im fairly new myself and have found it very helpful.

I just wanted to let you know that I am also on Pred. and just got my prescription for Imuran filled the other day and will be starting it soon.  I will be taking 40mg Pred. and 150mg Imuran.  From what I can see, it is fairly common to be on both but usually when you start Imuran, I do believe that you start tappering off the Pred.  My GI told me that once I start Imuran that I am to tapper off 5mg a week from the Pred.

Anyways, hope that helps.

Keep smiling.

Just diagnosed Aug. 14/07
Asacol 8 / day (5-Aminosalicylic Acid 400mg)
Pred. 50mg
Cortafoam (butt mousse, not emima)
Florastor Probiotic

Another UC wife
Veteran Member

Date Joined Jun 2007
Total Posts : 2111
   Posted 10/28/2007 6:25 PM (GMT -6)   
In our case my husband became steroid dependant. After almost a year of being on this and that and landing in the hospital it was evident that the Imuran (Azathioprine) needed to be given a try. He was put on a low dose of 75 mg along with 40 mg of prednisone. (To jump start the imuran I think she said)

After 4 1/2 months on the Imuran and starting a tapering he showed signs of improvement. It was decided when he got to the 15 mg to stay on it while we were away for 2 weeks as we were out of the country. We are now back and resuming the tapering by 2 1/2 mg every 10 days. So far so good. His Imuran dose was increased to 150mg as the 75 was a low dose even though he was responding. It is felt the 150 dose (he could be as high as 200 if need be) will give even better results.

The Dr is monitoring it closely and requires blood tests every month to monitor and then he will write a prescription for another month and so on for one year. After that maybe a prescription every 6 months from the sound of things.

Not sure if and when he is in a full remission if the imuran is decreased at all and if the 12 asacol per day is decreased as well. From some of what I have read here it seems that could be the case. We are not at that point yet but will inquire down the road.

As you can see from the signature line here he is on a lot of meds. We just did two weeks of his meds....good thing they make some of those pill containers with large enough compartments!!!!

Fortunately the only side effect at the moment is his face breaking out. Previously that was from the prednisone but I think the imuran is also impacting that. Too bad I thought once he got off the prednisone that would clear up. He never had acne - always great skin and complexion since I met him in 1968. At 61 he's looking like a pimply

61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07  Oct 07 feeling quite normal most days.  150mg Imuran 15 mg prednisone & tapering, 12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 20 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs  Morphine Sulf 15 mg twice daily)Cortifoam enemas AM & PM, folic acid 1mg, Fosamax 1x month

Veteran Member

Date Joined Jul 2007
Total Posts : 2148
   Posted 10/29/2007 8:27 AM (GMT -6)   
I'm on 100 mg of Azathioprine (Imuran) and 60 one day 40 the next day etc. of Prednisone. Yes, I worry too, I am just starting to feel better I think from the pred or the hydrocortisone and it is such a relief, but I have about 4 more mos of the prednisone (for my kidney) and possibly starting remicade next month.

I have a notebook now to keep track of everything.
Beth, 32
UC Diagnosed March 2000
Azathioprine 100mg 1xday;Remicade tests pending;Hydrocortisone enemas 1xday;Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Potassium 600mg 1xday, Probiotics.
Minimal Change Disease (Kidney Disorder) Diagnosed Sept 2007
Prednisone 60mg 1xday, Simvastatin 20mg 1xday, Diovan 80mg 1xday. Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.

Veteran Member

Date Joined Jan 2007
Total Posts : 1015
   Posted 10/29/2007 9:52 AM (GMT -6)   
I am steroid dependent and must stay on pred until the imuran kicks in. When i taper the pred i flare. Hopefully iwill be able to get off of the pred with help of imuran. From what i have heard it is pretty common to use pred until imuran kicks in (it can takes some months to see results from imuran0
Kelly, 29

Left sided UC diagnosed 1/98 age 19, Pan colitis diagnosed 1/07
Currently on 4x3 Asacol, Rowasa every other night, 15 mg pred. until immuran kicks in...
75mg Imuran starting 8/23/07---bumped to 100mg 10/8/07
Prontonix once daily for acid reflux, zofran twice daily for nausea

Regular Member

Date Joined Jun 2007
Total Posts : 54
   Posted 10/29/2007 10:42 AM (GMT -6)   
The reason for both meds is that the Imuran takes a while to work. If you are flaring, the Imuran will not help immediately. It can take a few months. The prednisone is continued or started so that you can get relief from the flare. Then, after a period of time, the MD will begin to taper the prednisone to see if the Imuran is keeping you in remission without the prednisone. I was on prednisone, Imuran, and Remicade for 3 months before finally getting to a point where I am almost done with the prednisone (5mg and counting!). Without the prednisone while waiting for the imuran and remicade to kick in I would have been miserable.

UC diagnosed 2004

Asacol 9 tablets daily

Canasa PRN/ Currently 1x in evening

Prednisone- 30 mg as of 6/8/07, Increased to 50mg 6/18/07, 10mg as of 10/15/07

Lialda 4 tablets daily

Multi vitamins

Azathioprine 50mg

4th Remicade Infusion 11/21/07

New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, September 18, 2018 6:07 PM (GMT -6)
There are a total of 3,004,433 posts in 329,145 threads.
View Active Threads

Who's Online
This forum has 161738 registered members. Please welcome our newest member, Rosheen.
193 Guest(s), 6 Registered Member(s) are currently online.  Details
goshawk, Kent M., 3timechamp, Tudpock18, Woodduck12, Korissa