In our case my husband became steroid dependant. After almost a year of being on this and that and landing in the hospital it was evident that the Imuran (Azathioprine) needed to be given a try. He was put on a low dose of 75 mg along with 40 mg of prednisone. (To jump start the imuran I think she said)
After 4 1/2 months on the Imuran and starting a tapering he showed signs of improvement. It was decided when he got to the 15 mg to stay on it while we were away for 2 weeks as we were out of the country. We are now back and resuming the tapering by 2 1/2 mg every 10 days. So far so good. His Imuran dose was increased to 150mg as the 75 was a low dose even though he was responding. It is felt the 150 dose (he could be as high as 200 if need be) will give even better results.
The Dr is monitoring it closely and requires blood tests every month to monitor and then he will write a prescript
ion for another month and so on for one year. After that maybe a prescript
ion every 6 months from the sound of things.
Not sure if and when he is in a full remission if the imuran is decreased at all and if the 12 asacol per day is decreased as well. From some of what I have read here it seems that could be the case. We are not at that point yet but will inquire down the road.
As you can see from the signature line here he is on a lot of meds. We just did two weeks of his meds....good thing they make some of those pill containers with large enough compartments!!!!
Fortunately the only side effect at the moment is his face breaking out. Previously that was from the prednisone but I think the imuran is also impacting that. Too bad I thought once he got off the prednisone that would clear up. He never had acne - always great skin and complexion since I met him in 1968. At 61 he's looking like a pimply teenager...lol.
61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07 Oct 07 feeling quite normal most days. 150mg Imuran 15 mg prednisone & tapering, 12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 20 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs Morphine Sulf 15 mg twice daily)Cortifoam enemas AM & PM, folic acid 1mg, Fosamax 1x month