Posted 11/10/2007 2:22 AM (GMT -6)
i was at the my GI the other day and we were chatting about foods... (as u do)...
and he gave me this printout of a bunch of medical study articles on "Dietary Factors in the Modulation of Inflammatory Bowel Disease Activity"
so i typed out the part on POTATOES. (cuz i noticed on lots of other posts, a lot of us love potatoes even though they cause problems)
for all of you (like me) who absolutely can't do without potatoes... here is a reason why they hurt us so bad. i don't know about you, but im still gonna eat them. i just can't help myself.
here it is:
Epidemiologic studies have indicated that the prevalance of IBD is directly correlated to consumption of fried potato products.
Altered intestinal permeability is believed by some to play a key role in the initiation and propagation of the inflammatory process. It is thought that bacterial products or even bacteria themselves may penetrate this altered epithelial barrier, activating the intestinal immune system. Potatoes have a high concentration of glycoalkaloids, specifically alpha-solanine and alpha-chaconine. These molecules "permeabilize cholesterol-containing membranes" and this is believed to alter the intestinal epithelial barrier. These glycoalkaloids are concentrated when potatoes are fried.
These molecules are present in potato as a sort of defense mechanism for the potato plant, playing a key role in defending the plant against fungi, bacteria, and parasites. However, these molecules have been shown to adversely affect the permeability of epithelial cells in the intestine, and this may aggrevate IBD. These compounds have been shown to adversely affect the intestine permeability in an IL-10 deficient mice model of colitis, but not in normal mice, suggesting that those patients with IBD may be predisposed to this adverse effect.
so, there you go.. just an interesting article to share..and a bit of a bummer.
**oh, and another quick note... omega-6 fatty acids are bad for IBD. Omega-3's are good.
sources of omega 3's include: fish, fish oil, algae, walnuts, leafy green vegetables, flax and canola oils.
sources of omega 6's include: corn, soy, primrose, sunflower and safflower oils, red meat and borage.
(omega-6 fatty acids are the precursor to sythesis of arachidonic acid, which is degraded into powerful mediators of inflammation by phospholipase A2 in the colon) so in other words, don't eat omega-6 fatty acids.
31 year old female - diagnosed UC in 2000
started as proctitis and now is pancolitis..
this current year long flare is now severe on left side only.
just got out of hospital with 200mg of hydrocortisone injections a day
**3 weeks out of hospital and have no colitis symptoms... normal bm's only 1x a day + no blood
50mg prednisone 1x with lunch or breakfast
50mg imuran 1x 8pm stopped it to try and have a baby
2x 500mg mesalazine 2x day + night
2.5mg endone (oxycontin) every 6-8 hours for pain
25mg tomazepam for sleeping
VSL#3 didnt work
Aloe Elite didnt work
Budesonide 9mg day didnt work
ive lost 40+lbs and my legs look like sticks ... ewww