i was at the my GI the other day and we were chatting about
foods... (as u do)...
and he gave me this printout of a bunch of medical study articles on "Dietary Factors in the Modulation of Inflammatory Bowel Disease Activity"
I tried to go to the site http://www.medscape.com/viewarticle/553039 but you need to be a doctor to sign up for these...
so i typed out the part on POTATOES. (cuz i noticed on lots of other posts, a lot of us love potatoes even though they cause problems)
for all of you (like me) who absolutely can't do without potatoes... here is a reason why they hurt us so bad. i don't know about you, but im still gonna eat them. i just can't help myself.
here it is:
Epidemiologic studies have indicated that the prevalance of IBD is directly correlated to consumption of fried potato products.
Altered intestinal permeability is believed by some to play a key role in the initiation and propagation of the inflammatory process. It is thought that bacterial products or even bacteria themselves may penetrate this altered epithelial barrier, activating the intestinal immune system. Potatoes have a high concentration of glycoalkaloids, specifically alpha-solanine and alpha-chaconine. These molecules "permeabilize cholesterol-containing membranes" and this is believed to alter the intestinal epithelial barrier. These glycoalkaloids are concentrated when potatoes are fried.
These molecules are present in potato as a sort of defense mechanism for the potato plant, playing a key role in defending the plant against fungi, bacteria, and parasites. However, these molecules have been shown to adversely affect the permeability of epithelial cells in the intestine, and this may aggrevate IBD. These compounds have been shown to adversely affect the intestine permeability in an IL-10 deficient mice model of colitis, but not in normal mice, suggesting that those patients with IBD may be predisposed to this adverse effect.
so, there you go.. just an interesting article to share..and a bit of a bummer.
**oh, and another quick note... omega-6 fatty acids are bad for IBD. Omega-3's are good.
sources of omega 3's include: fish, fish oil, algae, walnuts, leafy green vegetables, flax and canola oils.
sources of omega 6's include: corn, soy, primrose, sunflower and safflower oils, red meat and borage.
(omega-6 fatty acids are the precursor to sythesis of arachidonic acid, which is degraded into powerful mediators of inflammation by phospholipase A2 in the colon) so in other words, don't eat omega-6 fatty acids.