interesting fact for potato lovers

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kazygirl
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Date Joined Sep 2007
Total Posts : 955
   Posted 11/10/2007 12:22 AM (GMT -7)   
i was at the my GI the other day and we were chatting about foods...  (as u do)...
 
and he gave me this printout of a bunch of medical study articles on "Dietary Factors in the Modulation of Inflammatory Bowel Disease Activity"
 
I tried to go to the site http://www.medscape.com/viewarticle/553039 but you need to be a doctor to sign up for these...
 
so i typed out the part on POTATOES.  (cuz i noticed on lots of other posts, a lot of us love potatoes even though they cause problems)
 
for all of you (like me) who absolutely can't do without potatoes... here is a reason why they hurt us so bad.  i don't know about you, but im still gonna eat them. i just can't help myself.
 
here it is:
 
Epidemiologic studies have indicated that the prevalance of IBD is directly correlated to consumption of fried potato products.

Altered intestinal permeability is believed by some to play a key role in the initiation and propagation of the inflammatory process. It is thought that bacterial products or even bacteria themselves may penetrate this altered epithelial barrier, activating the intestinal immune system. Potatoes have a high concentration of glycoalkaloids, specifically alpha-solanine and alpha-chaconine. These molecules "permeabilize cholesterol-containing membranes" and this is believed to alter the intestinal epithelial barrier. These glycoalkaloids are concentrated when potatoes are fried.

These molecules are present in potato as a sort of defense mechanism for the potato plant, playing a key role in defending the plant against fungi, bacteria, and parasites. However, these molecules have been shown to adversely affect the permeability of epithelial cells in the intestine, and this may aggrevate IBD. These compounds have been shown to adversely affect the intestine permeability in an IL-10 deficient mice model of colitis, but not in normal mice, suggesting that those patients with IBD may be predisposed to this adverse effect.
 
___________
 
so, there you go..  just an interesting article to share..and a bit of a bummer.
 
 
**oh, and another quick note... omega-6 fatty acids are bad for IBD.  Omega-3's are good.
 
sources of omega 3's include: fish, fish oil, algae, walnuts, leafy green vegetables, flax and canola oils.
sources of omega 6's include: corn, soy, primrose, sunflower and safflower oils, red meat and borage.
 
(omega-6 fatty acids are the precursor to sythesis of arachidonic acid, which is degraded into powerful mediators of inflammation by phospholipase A2 in the colon)  so in other words, don't eat omega-6 fatty acids.
 
31 year old female - diagnosed UC in 2000
started as proctitis and now is pancolitis..
this current year long flare is now severe on left side only.
just got out of hospital with 200mg of hydrocortisone injections a day
**3 weeks out of hospital and have no colitis symptoms... normal bm's only 1x a day + no blood
 
50mg prednisone 1x  with lunch or breakfast
50mg imuran 1x  8pm stopped it to try and have a baby
2x 500mg mesalazine 2x day + night
2.5mg endone (oxycontin) every 6-8 hours for pain
25mg tomazepam for sleeping
VSL#3 didnt work
Aloe Elite didnt work
Budesonide 9mg day didnt work
ive lost 40+lbs and my legs look like sticks ... ewww
 


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 11/10/2007 12:29 AM (GMT -7)   
From what I undrstand you have to have the 3 and 6 to balance out the 9...I take 3-6-9 and have had no problems.

Best to eat those potatoes mashed or baked rather then fried and most definitely un-processed since we are suppose to avoid all processed foods/beverages.

:)
My bum is broken....there's a big crack down the middle of it!  LOL  :)


1s
Regular Member


Date Joined Sep 2007
Total Posts : 49
   Posted 11/13/2007 3:26 AM (GMT -7)   
thats a pretty interesting article. thanks for sharing
left sided
prescribed lialda
take herbal meds instead


Delarge
Regular Member


Date Joined Mar 2007
Total Posts : 157
   Posted 11/13/2007 4:32 AM (GMT -7)   
I doubt potato consumption contributes significantly to the pathogenesis of IBD.

kazygirl
Veteran Member


Date Joined Sep 2007
Total Posts : 955
   Posted 11/13/2007 4:34 PM (GMT -7)   
no one is saying that is "contributes significantly to the pathogenesis of IBD"... just an article on how potatoes might aggrivate the colon of people with IBD when they eat them. i think your reading a bit too much into it mate.
31 year old female - diagnosed UC in 2000
started as proctitis and now is pancolitis..this year long flare is now severe on left side only.
**3 weeks out of hospital/no colitis symptoms... normal bm's only 1x a day + no blood
50mg prednisone 1x  with lunch or breakfast
50mg imuran 1x  8pm stopped it to try and have a baby
2x 500mg mesalazine 2x day + night
VSL#3 didnt work
Aloe Elite didnt work
Budesonide 9mg day didnt work
ive lost 40+lbs and my legs look like sticks ... ewww
 


GardenerJames
Veteran Member


Date Joined Jan 2006
Total Posts : 616
   Posted 11/13/2007 5:50 PM (GMT -7)   
That's funny, when I eat a lot of fried potatos at restaurants etc... like when I'm travelling, things firm up. but when I eat potatos in stew at home or when I make them it seems to cause more problems for me.
Yet another random UC thing!!!
James
Current Meds www.myspace.com/gardenerjames

Asacol 4 tabs 2x daily
Forvia once a day
Probiotic twice daily
Methotrexate 3 pills once a week
Actonel once a week
Calcium supp.
Omega-3 once daily
Tenth Remicade infusion Early December


Delarge
Regular Member


Date Joined Mar 2007
Total Posts : 157
   Posted 11/13/2007 5:52 PM (GMT -7)   
kazygirl said...
no one is saying that is "contributes significantly to the pathogenesis of IBD"... just an article on how potatoes might aggrivate the colon of people with IBD when they eat them. i think your reading a bit too much into it mate.


Your post did to a degree. ;)

"Epidemiologic studies have indicated that the prevalance of IBD is directly correlated to consumption of fried potato products."

tru-believer
Regular Member


Date Joined Dec 2006
Total Posts : 329
   Posted 11/13/2007 6:19 PM (GMT -7)   
 
 
   PB 4 is right on the issue.  Its not the potato, its
   the oil its cooked in and the way it is cooked.
   Fast food processed potatoes are the source
   of the inflammatory regimen.

SwollenColon
Regular Member


Date Joined Nov 2006
Total Posts : 190
   Posted 11/13/2007 9:22 PM (GMT -7)   
I try my best to avoid anything fried.....it seems to make me gassier than usual. If I take 4 Beano pills, I can eat a steak, baked potatoe, a roll or two, and have a glass of unsweetened tea, and have no problems. I rarely eat french fries anymore, and only have homemade pan-fried potatoes every once in a while. I've always thought the starch in the potatoes was what made them bad for IBD'ers.

quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 11/14/2007 3:19 AM (GMT -7)   
Potatoes in any form don't bother me at all....except the ones from Montana's with all that garlic in them...bleh!
I even eat the skins on baked potatoes.

q
*Heather*Status:mini flare June 23* 6asacol daily+ Salofalk (tapered every 4th night)
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals 
~Probiotic 2 (Natural Factors Protec) + 1 (Primadophilus Reuteri) at bedtime
~Natural Factors Multi Digestive Enzymes with supper
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 23549
   Posted 11/14/2007 5:29 AM (GMT -7)   
Potatos don't bother me either nor french fries. Good thing because I LOVE potatoes and everything that can be made from them. Goes to show how individualist we all are.

It's a good article kazygirl because there are many here that can't tolerate potatoes and now they know why :)
 @--->--SHERRY--<---@
Left sided Uc -'92 - Colazal, 6mp, Prilosec, Biotin, Forvia, Pro-Bio 
Allergies - Singulair, Astelin(got the script - just haven't tried it yet!)
Secondary Reynauds Syndrome - '04 - Norvasc
Fibromyalgia - '06 
PLEASE HELP HEALINGWELL CONTINUE TO HELP OTHERS BY CLICKING HERE: DONATE
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schrek-chewbacca hunk
Veteran Member


Date Joined Jun 2005
Total Posts : 2666
   Posted 11/14/2007 8:11 AM (GMT -7)   
Funny, potatoes calm my colitis (bad for my diabetes!) but all the white foods are comfort foods that help me in flare.
 
we're all different!
 
bob

UC Fighter
Regular Member


Date Joined Oct 2007
Total Posts : 89
   Posted 11/14/2007 3:39 PM (GMT -7)   
Crap, I just ate Hash Browns this morning. Well, we'll see if it rips me up or not.
Current Prescriptions:
 
40 mg 30 mg Prednisone per day, 1 x per day
Sulfasalazine, 3x per day
   1500mg @ Breakfast, 1500mg @ Lunch, 1000mg @ Dinner
1 Mesalamine Enema per night


kazygirl
Veteran Member


Date Joined Sep 2007
Total Posts : 955
   Posted 11/14/2007 10:19 PM (GMT -7)   
see, i can't tell if they bother me or not. i always have symptoms so i never know. i eat them anyway cuz they are my favorite. i luv them..
31 year old female - diagnosed UC in 2000
started as proctitis and now is pancolitis..this year long flare is now severe on left side only.
**3 weeks out of hospital/no colitis symptoms... normal bm's only 1x a day + no blood
50mg prednisone 1x  with lunch or breakfast
50mg imuran 1x  8pm stopped it to try and have a baby
2x 500mg mesalazine 2x day + night
VSL#3 didnt work
Aloe Elite didnt work
Budesonide 9mg day didnt work
ive lost 40+lbs and my legs look like sticks ... ewww
 


UC Fighter
Regular Member


Date Joined Oct 2007
Total Posts : 89
   Posted 11/14/2007 11:36 PM (GMT -7)   
I had a pretty hard time tonight. I'll blame the taters.
Current Prescriptions:
 
40 mg 30 mg Prednisone per day, 1 x per day
Sulfasalazine, 3x per day
   1500mg @ Breakfast, 1500mg @ Lunch, 1000mg @ Dinner
1 Mesalamine Enema per night


mudua
Regular Member


Date Joined Apr 2007
Total Posts : 459
   Posted 11/15/2007 2:40 PM (GMT -7)   
My doctor who is of Indian origin told me 3 years ago that some researchers suspected french fries as one of the causes of U.C. He told me that the U.C started becoming a problem in countries like South Africa the moment apartheid fell and fast fast outlets like McDonalds started operating in South Africa. The same thing happened in India. Is it a coincidence that U.C in both South Africa and India is very prevelant in the big cities and not in the villagers where these fast food outlets do not exists?

cap'n colitis
Regular Member


Date Joined Nov 2007
Total Posts : 51
   Posted 11/15/2007 3:06 PM (GMT -7)   
(spoken like carl from sling blade) : I reckin french fried patayters don't bother my bottom much... Mmmhmmmm

stm177
Regular Member


Date Joined Jul 2007
Total Posts : 90
   Posted 11/15/2007 3:15 PM (GMT -7)   
Fast food or potato chips can bring on a flare in me! Now I know why! :-)
Proctitis - diagnosed April 2007 (symptoms starting in October 2006)

Flares treated with Rowasa enemas

Mild food diet (chicken, rice, collard greens, no sugar, no corn, no beef/pork, etc)


mudua
Regular Member


Date Joined Apr 2007
Total Posts : 459
   Posted 11/16/2007 11:45 AM (GMT -7)   

 

Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease.

Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

BACKGROUND: Disruption of epithelial barrier integrity is important in the initiation and cause of inflammatory bowel disease (IBD). Glycoalkaloids, solanine (S), and chaconine (C) are naturally present in potatoes, can permeabilize cholesterol-containing membranes, and lead to disruption of epithelial barrier integrity. Frying potatoes concentrates glycoalkaloids. Interestingly, the prevalence of IBD is highest in countries where fried potatoes consumption is highest. OBJECTIVE: To further understand the role of potato glycoalkaloids on intestinal barrier integrity, we examined the effect of varying concentrations of solanine and chaconine on intestinal permeability and function. METHODS: Solanine (0-50 microM), chaconine (0-20 microM), or a 1:1 mixture (0-20 microM) were exposed to T84 cultured epithelial monolayers for varying periods of time to determine concentration response effect on epithelial permeability. Next, a 1:1 mixture (5 microM) of solanine-to-chaconine (C:S) was exposed to sheets of normal murine small intestine, mounted in Ussing chambers, from control and interleukin-10 gene-deficient mice to determine whether glycoalkaloids affected intestine from mice with a genetic predisposition for IBD greater than controls. Finally, the effects of glycoalkaloids on colonic histologic injury were examined in mice orally fed amounts of glycoalkaloids that would normally be consumed in a human diet. RESULTS: Glycoalkaloids embedded and permeabilized the T84 monolayer epithelial membrane bilayer in a concentration-dependent fashion, with C:S > C > S. In vitro Ussing chamber experiments also illustrated a concentration-dependent disruption of intestinal barrier integrity in animals with a genetic predisposition to develop IBD, but not in control animals. Similarly, in vivo oral feeding experiments demonstrated that C:S ingestion, at physiologic concentrations, aggravated histologic colonic injury in mice genetically predisposed to developing IBD. CONCLUSION: Concentrations of glycoalkaloids normally available while eating potatoes can adversely affect the mammalian intestine and can aggravate IBD.

PMID: 12479649 [PubMed - indexed for MEDLINE]


UC Fighter
Regular Member


Date Joined Oct 2007
Total Posts : 89
   Posted 11/16/2007 1:42 PM (GMT -7)   
It's McDonalds fault!!! Let's sue!
;)
Current Prescriptions:
 
40 mg 30 mg Prednisone per day, 1 x per day
Sulfasalazine, 3x per day
   1500mg @ Breakfast, 1500mg @ Lunch, 1000mg @ Dinner
1 Mesalamine Enema per night


tjf
Veteran Member


Date Joined Dec 2005
Total Posts : 3238
   Posted 11/16/2007 1:45 PM (GMT -7)   
Not McDonalds!!! It is my weakness!!!!! Baked potatoes have always been a 'safe' food for me.
Tabitha (Tab)

100mg Azathioprine, 2 Fibercon, Colazal-6 a day, Acidopholis Pearls, Prilosec OTC

http://www.healingwell.com/donate
Co-Moderator UC Forum


UC Fighter
Regular Member


Date Joined Oct 2007
Total Posts : 89
   Posted 11/16/2007 1:53 PM (GMT -7)   
I hear you there. I LOVE McDs.
Funny thought, I ate at McDs all the time during my nine year remission. Not a single bad occurance.
Current Prescriptions:
 
40 mg 30 mg Prednisone per day, 1 x per day
Sulfasalazine, 3x per day
   1500mg @ Breakfast, 1500mg @ Lunch, 1000mg @ Dinner
1 Mesalamine Enema per night


quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 11/17/2007 12:23 AM (GMT -7)   
French fries don't cause UC....oh brother

q
*Heather*Status:mini flare June 23* 6asacol daily+ Salofalk (tapered every 4th night)
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals 
~Probiotic 2 (Natural Factors Protec) + 1 (Primadophilus Reuteri) at bedtime
~Natural Factors Multi Digestive Enzymes with supper
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 23549
   Posted 11/17/2007 6:06 AM (GMT -7)   
I've 3 bad experiences with McD's. I was pregnant with my son and was going to a comedy concert so we stopped to get a bite to eat. I found a large plastic chunk in my Big Mac - gross! And the other time was when we had to travel to Missouri for my gpa's funeral and I must of got a bad burger or something because I had major major pain that came in waves and massive D. I should've gone to the doctor but I wasn't thinking right because of the grief over losing my grandfather. The pain lasted about a month off and on. Oh and another time we were traveling back from Missouri, later in that year to help move my gma and I had 2 cheeseburgers, went to open the bun to take out the onions and a spider crawled out!
 @--->--SHERRY--<---@
Left sided Uc -'92 - Colazal, 6mp, Prilosec, Biotin, Forvia, Pro-Bio 
Allergies - Singulair, Astelin(got the script - just haven't tried it yet!)
Secondary Reynauds Syndrome - '04 - Norvasc
Fibromyalgia - '06 
PLEASE HELP HEALINGWELL CONTINUE TO HELP OTHERS BY CLICKING HERE: DONATE
@--->--Moderator for Allergies/Asthma and Co-moderator for UC--<---@
 
 
 
 

 
 


tjf
Veteran Member


Date Joined Dec 2005
Total Posts : 3238
   Posted 11/17/2007 6:22 AM (GMT -7)   
Now that's just nasty!
Tabitha (Tab)

100mg Azathioprine, 2 Fibercon, Colazal-6 a day, Acidopholis Pearls, Prilosec OTC

http://www.healingwell.com/donate
Co-Moderator UC Forum

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