Can someone tell me HOW Imuran works?

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DeniseW
Regular Member


Date Joined Nov 2005
Total Posts : 346
   Posted 11/12/2007 10:30 AM (GMT -7)   
Imuran is a chemotherapy drug.  But I was tested to see how much of the "enzyme" I already had in my system.  Turns out I have a lot already and can only take a half dose.  What exactly does that means that my body is already producing?  And what is it suppose to do in there?  Beyond it being an immunosupressant to keep me from making antibodies to the remi of course...
I'm kinda clueless and I get up so early for the remi treatments I forget to ask my doc when I'm there.  Not sure he'd explain it where I could get it anyway.
 
Thanks.
dx 4/05 with pancolitis UC after birth of my second child... meds worked randomly
SCD and vit e enema remission for 18 months and had another drug free baby 10/06
Let flare get out of control and even steroids wouldn't work 7/07 - docs wanted surgery
lialda x4 daily and started remicade 10/26/07
 
 


UC Dude
Regular Member


Date Joined Aug 2005
Total Posts : 438
   Posted 11/12/2007 5:38 PM (GMT -7)   
I dont think its chemo, rather an immunosupressant (sp) that is given to transplant patients. It couteracts our over active immune systems. Of course this is simple.

Google it if you want more info..
 


DeniseW
Regular Member


Date Joined Nov 2005
Total Posts : 346
   Posted 11/12/2007 9:27 PM (GMT -7)   
It's a chemotherapy drug they just don't use much anymore. I couldn't seem to find anything on HOW it works, just what it's used for. Guess I'll have to keep looking.
dx 4/05 with pancolitis UC after birth of my second child...
18 months of vit e enema and scd remission
Flare since 7/07...almost to surgery, now almost well through mostly natural stuff
Trying to make up the difference with...
Lialda 4/day
Remicade 10/26, 11/09, next 12/3
Imuran 50mg at night 11/11
 
 


UCreallySUCKS
Regular Member


Date Joined May 2006
Total Posts : 260
   Posted 11/12/2007 10:08 PM (GMT -7)   
I've wondered the same thing, but everytime I do a search on it, I come up with the same answer - "how Imuran works is unknown".  Guess as long as it works, it really doesn't matter, but I still would like to know exactly how it works.

---Nathan---  31 yr old male
Diagnosed May 2006 w/severe UC (pancolitis)
Currently in mild flare
2 400mg Asacol 4X day
10mg Prednisone
1 multivitamin/day
2 grams calcium/day
75mg Imuran/day
100mg Tramadol/day for abdominal pain (as needed)
1 Fioricet ever 4 hrs as needed for severe migraines


Delarge
Regular Member


Date Joined Mar 2007
Total Posts : 157
   Posted 11/13/2007 4:42 AM (GMT -7)   
UC Dude said...
I dont think its chemo, rather an immunosupressant (sp) that is given to transplant patients. It couteracts our over active immune systems. Of course this is simple.

Google it if you want more info..


Chemotherapy = chemical + therapy.

Azathioprine limits the proliferation of certain cells, notably leukocytes (white blood cells), through purine inhibition. In effect reducing one's immunological status, limiting the body's ability to fight infection.
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