The frustrating thing about Imuran and 6MP is that it can be many months before you sense if they are making any positive impact at all. However, clearly for some they can be very helpful. I am keeping mine up for now but I can't say it really helps. For what it's worth, I seem to be benefiting from the pig whipworm eggs (TSO) which is not very accepted by the medical community yet, and happens to be very expensive. But that's what I mean by not closing doors on alternative and/or still not generally accepted treatments. Also, many who don't do well on one 5asa med do fine on others, so you may want to try the others if you haven't already (Colazal, Dipentum, Asacol, and sulfasalazine).
Pancolitis dx'd 1986, full med-free remission 88-97
Flaring or simmering ever since
10 20 17.5 15 12.5 mg pred, 100 mg Imuran
Probiotics (Primal Defense and others), TSO
Turmeric/circumin, fish oil, many vits/minerals
Lower-carb version of Specific Carb Diet (SCD)