Raised CRP - What could it mean?

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Regular Member

Date Joined Oct 2007
Total Posts : 23
   Posted 11/16/2007 9:21 AM (GMT -6)   
Hopefully somebody will be able to help me with this.  It showed up on my last blood test a month ago that my CRP was up to 7.6 but I have been having no bowel symptoms.  The Consultant asked me to have a repeat and said if it went up again he was going to look at putting me on Azathioprine.  I have had a repeat test done yesterday and it is now up 8.6 but am still having no problems or symptoms.  I'm really not keen to go down the Azathioprine route yet as I actually feel ok at present.
I was wondering if anyone knew if it could have anything do with my bones/joints.  Ever since I have came off the Prednisolone 4 months ago I have had daily problems with my fingers, wrists, elbows and ankles which on research sounds like a type of rheumatoid arthritis.  Could this be causing my raised CRP?  Does anyone have suggestions for me?
As always thanks for your help.
Medication:  Asacol 3 x 2 daily

Regular Member

Date Joined Nov 2005
Total Posts : 346
   Posted 11/16/2007 9:28 AM (GMT -6)   
I don't know what CRP really does, but I thought it measured inflammation in general. If that's the case, then it could very well be your joints.
Either way, if you don't feel bad, I wouldn't take it. Maybe up your asacol first? I know the docs are trying to keep the inflammation down so we don't get cancer. When I was feeling ok my doc told me I needed to stay on the asacol, or whatever she was pushing at the time, to keep down the inflammation I couldn't tell was there. I opted not to since I was pg and I thought that those mesalamines were making me ill (ie, could be causing the inflammation).
If it is your joints, the azathioprine might work systematically and help with that, though I agree it's not something I'd opt to go on either if I was feeling fine.
dx 4/05 with pancolitis UC after birth of my second child...
18 months of vit e enema and scd remission
Flare since 7/07...almost to surgery, now almost well through mostly natural stuff
Trying to make up the difference with...
Lialda 4/day... I don't know, 3 months maybe?
Remicade 10/26, 11/09, next 12/3
Imuran 50mg at night 11/11
Been there, tried that....

Another UC wife
Veteran Member

Date Joined Jun 2007
Total Posts : 2111
   Posted 11/16/2007 11:00 AM (GMT -6)   
I believe you can take up to 12 asacol per day and I agree with maybe trying that???? CRP is something I'm not up on either -- the Aza (imuran) from what I understand is something that is prescribed when alot of the "trial and error" routes have been exhausted. It is a heavy duty drug and one that made the difference for my husband but you are nowhere near what he was going through when it was finally decided he needed to go on it.

Now if he was put on it sooner might it have prevented such an awful flare???? I don't know the answer to that. Maybe your Dr realizes a pattern developing with you and wants to head it off????

Obviously don't take our advice exclusively - discuss with the Dr and do as much research as you can.

Such a shame that there is not a specific consistent way to treat this for everyone.

61 yr old male~Colitis 1st diagnosed Jan '05-cleared up within a few wks. Flared again in May '06 (now UC) & hospitalized 5/07-currently heading towards a remission. Osteopena of spine from prednisone DX 8/07  Oct 07 feeling quite normal most days.  150mg Imuran 15 mg prednisone & tapering, 12 Asacol, Lidocaine Hydrochloride Jelly 2%,multi vitamin, iron 1X day, DanActive, chewable calcium, Prilosec 20mg, enalapril 10mg, glipizide 5 mg, zocor 20 mg, baby aspirin, (Fentanyl pain patch 50mg 72 hrs  Morphine Sulf 15 mg twice daily)Cortifoam enemas AM & PM, folic acid 1mg, Fosamax 1x month

Elite Member

Date Joined May 2003
Total Posts : 30835
   Posted 11/16/2007 12:21 PM (GMT -6)   
Hope this helps.
*Heather*Status:mini flare June 23* 6asacol daily+ Salofalk (tapered every 4th night)
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 2 (Natural Factors Protec) + 1 (Primadophilus Reuteri) at bedtime
~Natural Factors Multi Digestive Enzymes with supper
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

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