I just got off Asacol (12 x 400mg a day) and started on Colazal yesterday.
I've been prescribed quite a high dose of 12 a day (2 x 6) but I need to get back on track soon so I'm going with the required dosage. I agree with Sherry that 1 Colazal should not have much of an effect on you. However, if you feel that it is giving you pain then I would recommend having a discussion with your GI specialist soon as you also don't want to make things worse by not taking an adequate dosage to reduce or slow down the inflammation/flare-up.
Rio, 31 yr old male - diagnosed with UC in 07/2006.
Alternative therapies for several months (SCD, ayurvedic treatments, chinese herbs, VSL#3): didn't work and became anaemic.
Canasa, 2 daily: remission for a month then flared up.
Completed first (6-week) tapered course of Pred in 10/07, flaring up since coming off it.
Currently on: 4800mg Asacol (6 x 400mg, twice a day) & Aloe Elite (not sure if it works).
Holding off from taking next dose of Pred as the side-effects were strong, but may have to give in if I'm not better soon.