If the taper is done under the guidance of his physician I would think the side effects would be minimal. I tapered off once and the side effects I experienced concerned my doctor and she believed I needed a couple more years on them. The second time I tapered, very slowly, I had no side effects. Is your husband following a tapering program? If the emotional impact is great he might want to taper more slowly. In any event I think a doctor should be involved.
dx proctitis in 1987
dx UC in 1991, was stable until 1998
1998 started prednisone, asacol, pentasa, nortriptylene, ativan, 6MP, rowasa enemas and suppositories, hydrocortisone enemas, tried the SCD diet, being a vegetarian, omega 3s, flax, pranic healing, yoga, acupuncture, probiotics
2000 lost all my B-12 stores and became anemic
2001 opted for j-pouch surgery- now living life med-free