50mg Imuran increment make difference?

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Veteran Member

Date Joined May 2007
Total Posts : 528
   Posted 11/23/2007 10:46 PM (GMT -6)   
Hey Gang - I have been gone for awhile from our website, and doing well on the whole. Got off pred 3 months ago and Imuran seems to have helped me. i was put on Imuran about 5 months ago, but my GI increased my dose slowly, over time, to make sure I could handle it. I am now taking 150mg, but only added the last 50mg about 2 months ago, so I am only getting the benefits of about 100mg (it took 4 months for imuran to start working for me, so I feel pretty confident that it takes my body awhile to start benefiting from the drug). i am starting to see some symptoms again, and of course my mind is now spinning, worrying that Imuran will fail me. but, then I realized that maybe I just need this next 50mg to kick in.... so, what i am wondering, for those of you on Imuran, have you seen a difference in the effectiveness of the drug at a different dose? in other words, do you feel there is a substantial difference between 100 mg. and 150 mg? I am hoping the answer is "yes," and my GI certainly thinks that 50mg increments make a difference, but i wanted to check you with guys since you have the actual experience.....

as always, many thanks and I hope you all are well.
Pancolitis dx 3/07
*12 Asacol/day
*150mg Imuran/day (steroid dependent)
Various vitamins, probiotics, fish oil.

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 11/24/2007 8:47 AM (GMT -6)   
I'm not on Imuran but 6mp and my GI has been increasing my dosages 25mg at a time. I know the dosing for Imuran and 6mp are different so I'm not sure how that compares. But yes, I do notice a difference with my 6mp increases. It takes a while for my body to start working with the new dose though. The last time he increased my dose, it took about a month and a half to start noticing an improvement.
~Left sided Uc -'92 - Colazal (9 daily), 6mp (50-100mgs), Prilosec, Biotin, Forvia, Pro-Bio, Hydrocortisone enemas**Unable to tolerate Asacol, Rowasa or Canasa** 
~Allergies - Singulair, Astelin(got the script - just haven't tried it yet!)~
~Secondary Reynauds Syndrome - '04 - Norvasc~
~Fibromyalgia - '06~
@--->--Moderator for Allergies/Asthma and Co-moderator for UC--<---@


Veteran Member

Date Joined Jul 2007
Total Posts : 2148
   Posted 11/25/2007 7:29 PM (GMT -6)   
well, I went from taking 100mg for two weeks to taking 200mg and have been on 200mg for 4weeks now. I don't notice anything different....(have been on azathioprine for 6 weeks in total).
Beth, 32
UC Diagnosed March 2000 (30 cenitmeters)
Azathioprine 200mg 1xday nightly;Hydrocortisone e's tapering, Calcium and Vit D 500mg 3xday, Multi Vit, Folic Acid 400mg 2xday, Probiotics.
Minimal Change Disease (Kidney Disorder) Diagnosed Sept 2007
Prednisone 60/40mg alt days 1xday, Simvastatin 20mg 1xday, Diovan 160mg 2xday. Potassium 600mg 2xday, Fosomax 70mg 1xweek. MCD may be from hypersensitivty to 5ASA drugs.

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