If you're tapering the asacol...I'd suggest you wait until you're off the pred.
If you're tapering pred...you'll have some relapse of symptoms...probably.
If you're tapering the pred AND asacol...don't do them at the same time..meaning don't lower the asacol on Monday and then lower the pred the same day. Figure in where it's not at the same time. Trial and error I guess....
When you taper the pred, you can to the alternating method so that it kind of kick starts the adrenal glands into producing the cortisol....like 5, 2.5, 5, 2.5...etc till 2.5, 2.5, 2.5.....etc.
If you're wanting to try the above method, then maybe do the asacol taper one pill every month or every 2 weeks.
I strongly....STRONGLY....suggest you do rectal 5ASA retention enemas to make sure the rectum (which is the first to inflame and the last to heal) stays less inflamed during your tapering method.
I tapered off asacol...and the enemas.....eventually realised it's just much easier to maintain by increasing and tapering the rectal meds and continue with the 6 asacol daily.
Your experience is the best teacher anyway....but do make your learning experience at least as wisely as you can. Common sense goes a long way and it'll lessen the frustration.
keep us posted as to how you're doing.
*Heather*Status:mini flare June 23* 6asacol daily+ Salofalk (tapered every 4th night)
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~Probiotic 2 (Natural Factors Protec) + 1 (Primadophilus Reuteri) at bedtime
~Natural Factors Multi Digestive Enzymes with supper
~Ranitidine,Pariet (reflux) Effexor XR 75mg; Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!