I think this study is really important. It shows that the immune system is "attacking" itself, but not for the reasons western medicine says. It is attacking itself because the immune system has been compromised by LPS. LPS uses the body's first line of defense, the mast cell to help them attach to our intestinal mucosa barrier. Once the barrier is disrupted, particles of food, bacteria, etc are all introduced to the body through holes in the gut mucosa. The immune system sees all these as foreign and induces inflammation.
Its a cheesy summary, but I thought I would try and paint a picture. This looks like a cycle to me, with the LPS initiating and perpetuating the situation. The reason it can perpetuate the situation is inflammation alters your bodies ability to produce IAP. I wonder if this might be one of the genetic problems, the ability to produce sufficient IAP.
Post Edited (DanthaMan) : 1/1/2008 10:54:01 AM (GMT-7)