Why do they prescribe Remicade before Humira?

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princesscolon
Veteran Member


Date Joined Apr 2006
Total Posts : 733
   Posted 12/22/2007 8:14 AM (GMT -7)   
Does Remicade "work better" or what?  It seems like GIs prescribe the Remicade a lot more than Humira.  I don't know why when Humira is cheaper and you can do it at home.  Does anyone know why?
Adrienne,27
Diagnosed with Left-sided Ulcerative Colitis 1995 at 15
Tried: Prednisone, Rowasa & Hydrocortisone Enemas, Proctofoam, Sulfasalazine, Asacol, Probiotics, Fish Oil, Canasa, Enotcourt, Colazol, Proctocort, Anamantle, etc...
Diagnosed with Ulcerative Proctitis with rectal fistula in 2004, put on Remicade
2007:Increased Remicade dosage-660mg every 6 weeks,diagnosed with Psoriatic Arthritis & Fibromyalgia
Current meds: Remicade 660mgs every 6 wks ( I may be developing antibodies?), Lomotil, Darvocet, Clorazepate, new meds: Prograf, Cymbalta, Lyrica


Eva Lou
Veteran Member


Date Joined Sep 2006
Total Posts : 3437
   Posted 12/22/2007 8:55 AM (GMT -7)   
Humira still is not approved for use in UC by the FDA, so many insurance companies will not cover it. And some GI's do not think it's ethically right to prescribe it, yet. Also, I think Remicade & Humira are pretty much the same thing (both biologics, Remi being chimeric, Humira being monoclonal) so one isn't necessarily any better than the other. I think if you develop antibodies to Remicade, Humira may work for you initially, as it's "all human", so to speak. I think I'd prefer getting the med infused by someone else, than myself giving the injections. Although if Remicade stops working for me, you bet I'll fight to try Humira!

diagnosed with UC '02
meds-
Asacol- 8 tabs/day
Remicade infusions
Imuran- 100mgs/day
Prednisone- 10mgs/day
 


GardenerJames
Veteran Member


Date Joined Jan 2006
Total Posts : 616
   Posted 12/22/2007 9:39 AM (GMT -7)   
I think my GI mentioned that Humira has not been working quite as well for people with UC as it has for Chron's. So basically they start you on Remicade and if it doesn't work they give humira a whirl if they can get it past your insurance company.
James
Asacol 4 tabs 2x daily www.myspace.com/gardenerjames
Forvia once a day
Probiotic twice daily
Methotrexate 3 pills once a week
Actonel once a week
Calcium supp.
1 mg Folic Acid daily
Omega-3 once daily
Eleventh Remicade infusion End of January


princesscolon
Veteran Member


Date Joined Apr 2006
Total Posts : 733
   Posted 12/22/2007 11:07 AM (GMT -7)   
I almost freaked out to hear Humira is not approved for UC, I didn't realize that. My insurance gives me a hard time as it is. However, I JUST got diagnosed with Psoriatic Arthritis, (which I don't think I have, I think it was a reaction to the Remicade but we'll see) Sooo, if my insurance won't approve Humira for the UC, I can get it from the Arthritis Center. LOL Maybe all those pains were worth it in a way.
Adrienne,27
Diagnosed with Left-sided Ulcerative Colitis 1995 at 15
Tried: Prednisone, Rowasa & Hydrocortisone Enemas, Proctofoam, Sulfasalazine, Asacol, Probiotics, Fish Oil, Canasa, Enotcourt, Colazol, Proctocort, Anamantle, etc...
Diagnosed with Ulcerative Proctitis with rectal fistula in 2004, put on Remicade
2007:Increased Remicade dosage-660mg every 6 weeks,diagnosed with Psoriatic Arthritis & Fibromyalgia
Current meds: Remicade 660mgs every 6 wks ( I may be developing antibodies?), Lomotil, Darvocet, Clorazepate, new meds: Prograf, Cymbalta, Lyrica


Hobo
Regular Member


Date Joined Jan 2006
Total Posts : 187
   Posted 12/24/2007 5:22 PM (GMT -7)   

I have not been responding to "normal" medications so my GI feels that I won't respond to Remicade.

She has prescribed Humira. I contacted my insurance company and they say they will cover it.


jujub
Forum Moderator


Date Joined Mar 2003
Total Posts : 10405
   Posted 12/24/2007 10:32 PM (GMT -7)   
It all depends on your coverage. A lot of policies specifically state they do not cover any treatments considered "experimental", including drugs not approved by the FDA for your condition. That's why I had to wait to go on Remicade, there was no way I could afford it on my own.
Judy
 
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Intolerant to Asacol and rectal mesalamine preparations.
On Prednisone then Entocort 2001-2006 with only short periods off. 
Current meds are Colazal, Azathioprine and Remicade.
In remission since April, 2006. Remicade has been my wonder drug.
 


superdeejayanna
Regular Member


Date Joined Jul 2007
Total Posts : 77
   Posted 12/25/2007 3:21 PM (GMT -7)   
My GI gave me the choice- Humira sounds easier
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