hi, I am 34 years old, female, just had my PFO closed 1 week ago through cardiac cath procedure, my PFO was 10mm, I had 2 TIA episodes back in OCt/NOv 07, very scary, am on Topamax for chronic migraines, and Plavix as well, Docs keeping me on both meds, and I also suffer from BiPolar Disorder. Topamax is also being used as a mood stabilizer for bipolar, and has been quite successful thus far. The procedure for the closure was done under general anastesia, so I didn't feel a thing. We went back and forth for several months about whether or not to do the closure, but being young, married, and having two small children, I didn't want to risk a full blown stroke or a heart attack, the thought of leaving the PFO open was not an option for me, especially because through blood tests I was found to be genetically resistant to both aspirin and Plavix! I have to take 1000mg of vitamin C daily along with my Plavix to help my body to absorb it, and I still do not get the full health benefit of the medication, so even on it, I still run the risk of throwing a clot, it just reduces my risk. I am recovering well, but I expected to hit the 1 week mark after the procedure and feel like a new person. Anyone out there recovering like me? I still tire easily, and have little flutters/palpatations, but from what I have read on other threads it seems to be par fpr the coarse. I sometimes get that feeling like a "chicken bone" is stuck in my chest and I can't get it out, but from what I hear it is just my brain not realizing the patch is supposed to be there, and in time my brain will forget that it is there. I hope that is true! My hole is 10mm, the patch is 20mm, so the patch itself is about the size of a quarter. I also have one other problem working against me-- I have a nickel allergy! I can't wear any jewelry that isn't gold or silver or I break out in a serious rash, but my doctor used a closure device called the Gore-helex, which has much less nickel- titanium or nitinol as they call it, and it is supposed to be safer. Anyone out there have the nickel allergy or know anything about it?