Question about statin drugs and how they work.

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Regular Member

Date Joined May 2009
Total Posts : 24
   Posted 11/23/2009 4:43 PM (GMT -6)   
Background: I am 71 yr old male. In 1987 my total cholestral was 237, at age 49. Today it is 266. Over the years I have had numerous stress tests and three angiograms done. the results were always the same, i.e. my arteries look fine with no signs of blockage. I have taken every statin on the market, and my legs hurt so bad the doctor took me off all of them.

My question is about the statin drugs. Realizing that the tests concentrate on the heart, and if there is blockage elsewhere, it would not show up, I wonder if these drugs prevent the formation of plaque or will they help desolve any that is there.

Anyone have any thoughts on this? The doctors I ahve asked (3 different heart specialist) do not seem to know, or at least do not tell me.
70 year old male
PSA of 5.1

3/9/09 robotic surgery

non nerve sparing surgery

5/5/09 PSA Non detectable

5/24/09 slowly regaining bladder control.

6/8/09 graduated to thinner liners at night and most of the day. Pads when doing physical work, or going out of house for short trips.

8/18/09 PSA Non detectable at <.03

8/27/09 PSA redone by Mayo Clinic at my request - Non-detectable at <.0.01

11/20/09 PSA Non detectable using the super sensitive method.

Veteran Member

Date Joined Oct 2009
Total Posts : 5022
   Posted 11/23/2009 5:21 PM (GMT -6)   
I don't tolerate statins either. That said, I read a report that found that people who don't tolerate statins quite often can take them once a day. My cardiologist agreed and I take Crestor 5 mg once a week now as a secondary med. For my primary cholesterol lowering med I take colestid granules which I mix in juice daily.

Veteran Member

Date Joined Jul 2009
Total Posts : 504
   Posted 12/9/2009 3:34 AM (GMT -6)   
Hi Charlierobert

The total is not the only key deciding risk factor

What does your HDL,LDL and Triglycerides look like

Did they ever do a lipid profile to drill down to see what and if there is a problem

If statins are not helping did you try the Tricor or Niacin (Niaspan) route ?
Age: 52
PSA (2008)=1.9
Biopsy on Jan 09, 2009
One (1) out of twelve (12) cores was positive, plus external nodule found
Gleason Score = 3+3
Surgery (Da Vinci, robotic prostatectomy): 4/7/09
Removed Catheter: 04/19/09
100% bladder control - Pad free 7/09
PSA 7/09 undetectable, under .0

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