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Regular Member

Date Joined Apr 2006
Total Posts : 141
   Posted 11/28/2013 1:26 PM (GMT -6)   
I had a TIA in April 2011. At that time the doctors did a lot of testing and found that I have a hole in my heart and believe a blood clot went through and caused the stroke.
They put me on cholesterol medication as well as Warafin. I suggested strongly to them they needed to take me off Warafin or I would stop it myself. They put me on Plavix which I have been on since August 2011. Within the past year they added another medication to make my blood pressure go up because I suffer from low blood pressure.

On my most recent blood tests they noted in the comments section that a "rare giant platelet" was seen. I'm thinking the Plavix caused this but no one I have spoken to has heard of this side effect being caused by Plavix or its generic. The doctor who does the clinical trial I am on said I should ask my primary doctor to see a hematologist which I will. I'm thinking I want the hole closed so I won't need medication.

Anyone out there heard of this side effect????

Elite Member

Date Joined Apr 2007
Total Posts : 32602
   Posted 11/28/2013 3:21 PM (GMT -6)   
Hello there,  I was tested for a TIA but nothing was ever found - no PFO. 
Patients who have had a stroke or transient ischemic attack (TIA) may be placed on some type of blood thinner medication, such as aspirin, plavix (clopidogrel), or coumadin (warfarin) to prevent recurrent stroke.
The risks and long-term benefits of using percutaneous occlusion devices to treat patients with PFO are not yet determined. This type of treatment generally is recommended only for patients taking medication to reduce their risk of blood clots who have a second stroke or transient ischemic attack (TIA, or "mini stroke") thought to be caused by PFO.
I would revisit your Dr. about repairing your PFO or discuss why you are not a candidate if this is the problem.
I wish you the best and let us know what the Dr. has to say.
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