It probably depends on your bloodwork and how far things are out of whack. Everyone is quite different. I take 4 standard strength Costco fish oil capsules a day, two in the morning, two at night. This is all I needed though in the fish oil dept, I have heard of other people having to take more. In one of the books the author mentions that people too often take just one fish oil capsule, that is not enough to do anything at all. There are other supplements as well.
The best book I have found on the subject is "Track Your Plaque" by Dr. William Davis. This cardiologist covers the correct diet, supplements, prescription drugs, and how to get all your lipoproteins in order to halt the progression of CAD as observed on a fast slice CT scan. He also updates information at his web site with the latest stuff. Other good books are "Before The Heart Attacks" by Dr. Superko, and "The Cardiovascular Cure" by Dr. Cooke. Three years ago my LDL was LDL 173, HDL 43, Tri 177. My levels now are LDL 49, HDL 61, Tri 53 through the use of diet, supplements, weight loss, exercise, and some prescription drugs.
Best of luck,