hi ET,geez sounds like you are really having problems. i take lisinopril for mey bp, but i do not have the problems you do with needing such high doses. even on a small dose though my hair is falling out and i am a women, so that is quite a drag. how high is your bp without the meds? all i can say is you really need to bone up on all the stuff you are on. that metoprolol will make you so tired and dizzy all day if you take it in the am. i had to stop taking it, quality of life meant more to me than feeling 80 years old everyday of my life. you are really on some large doses, sorry you cannot lower your bp any other way. do you have a weight problem? as far as insomnia is concerned it is because of anxiety over your new problems, i actually had to start taking a sleep aid, and glad to do it, three or 4 nites with no sleep will make you crazy.wish i had some better info for you, but the best i can offer is read up and do not settle for feeling this way.