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b-12 spots

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Posted 7/25/2006 9:16 AM (GMT -8)
:-)  there are just for your info, these little pills you buy at the store that are b-12 , you put them under your tongue. i take one everyday, helps boost energy, i thought you might like to know about them Aldo.
Posted 7/25/2006 10:11 AM (GMT -8)
Thanks, I needed that. A nurse just told me the same thing :) They are called sublingual B-12, right? I read about some B-12 patches, but was told these little pills are better. I gotsta get me some.....
Posted 7/25/2006 3:18 PM (GMT -8)
:-)  you can buy them at a grocery store. they are made by twin labs and are 500mcg,and they are called b 12 dots. good luck  they are very cheap also, like 7 bucks .
Posted 7/25/2006 6:32 PM (GMT -8)
I only have 2 bucks. Could they give me 2 bucks worth from the bottle? Ha ha ha. Thanks Dreamy :)
Posted 7/25/2006 8:27 PM (GMT -8)
I've been using the B12 sublingual for over a month now. I can't say I have noticed any difference and I am using 2 mg. 2 x a day.

Main reason I'm using it is for being on Nexium, it can cause B12 not to be absorbed in the stomach, so you could end up with a deficiency.

Hugs,
Faye
Posted 7/26/2006 3:32 AM (GMT -8)
Yes Faye, I believe that may be my problem also. I tested low for B-12 not so long ago, and I have taken the Nexium type meds for around 7 years. I got a B-12 shot 2 days ago, ouch! Thanks for the info :)

Rj
Posted 7/26/2006 4:31 PM (GMT -8)

:-)  what does sublingual mean, and is that the same thing i am taking? or is it a stronger type.

Posted 7/26/2006 6:17 PM (GMT -8)

From Wikipedia

Sublingual, literally 'under the tongue', from Latin, refers to a pharmacological route of administration in which certain drugs are entered directly into the bloodstream via absorption under the tongue. Many pharmaceuticals are prepared for sublingual administration. These commonly include cardiovascular drugs, steroids, barbituates, some enzymes and increasingly frequently, certain vitamins and minerals.

The principle behind sublingual administration is fairly simple. When a chemical comes in contact with the mucous membrane, or buccal mucosa, it diffuses into the epithelium beneath the tongue. This region contains a high density of blood vessels, and as a result, via osmosis, the substance quickly enters the blood stream at the sublingual artery. Quickly thereafter, the substance is carried by blood flow to the connected lingual artery, which takes up the chemical and translates it to its source: the carotid artery. This artery is connected directly to the brain.

In theory, sublingual routes of administration have certain advantages over simple oral administration. This route is often faster, and entering a drug into one's body sublingually ensures that the substance will only come in contact with the enzymes in saliva prior to entry into the bloodstream. Drugs otherwise orally administered must instead survive the incredibly hostile environment of the gastrointestinal tract. This may mean a much greater percentage of the original substance is degraded either by the myriad of enzymes in the GI tract, such as monoamine oxidase, or the strong acids it contains. Additionally, after GI absorption, the drug is sent to the liver where the drug may be extensively metabolized; this is known as the first pass effect of drug metabolism. Due to the degradative qualities of the stomach and intestine, or the solubility of the GI tract, certain substances, such as salvinorin A may only be administered orally via the sublingual route.

Posted 7/27/2006 4:07 PM (GMT -8)

:-)  my aren't you thorough, thanks.  aldo i take a proton pump inhitor(prilosec) that eliminates the acid in your stomach.  do you think it could be effecting my b-12 levels too, or is it a different product.  i read somewhere that it will keep you from absorbing nutrients, but if you take it after you have eaten, like after your food has already digested than you would get the benefits i would think. same with your nexium. iknow iknow, they tell you to take this stuff before you eat, heck with that, i have been taking it my way for several months and seem to be doing fine

 Makes sense to me anyway  bye

Posted 7/28/2006 3:03 AM (GMT -8)
Dream, I take prilosec also and I take it on an empty stomach to. You need to be aware about the B-12 not being broken down, because your stomach acids are reduced. That is why B-12 is not absorbed (reduced stomach acid). Acid in the stomach breaks B-12 down, then it is absorbed in the small intestine. I got a B-12 shot the other day, becaise my serum B-12 was low. I take 40mg of prescription prilosec each day. I think that I am repeating myself, but it's early :)

Oh yeah, good morning :)

Rj
Posted 7/28/2006 3:09 AM (GMT -8)
I didnt know about these b-12 spots things...hmmm,  Will have to check these out...thanks for the info dreamy
Posted 7/28/2006 4:32 PM (GMT -8)

:-)  sop Aldo, will the ones you put under your tongue work since you are not swallowing them? is that the point if subligil? sorry to ask again, but i think this is right. what about all the other vitamins i take, are they pointless because of the prilosec?  i usually take all my vitamins early,give them two hours to work then i will take the prilosec

Posted 7/28/2006 8:17 PM (GMT -8)
The concern is just for vitamin B-12, as far as I know. It takes stomach acid to break it down, before being absorbed by the small intestine. B-12 deficiencies have been documented in many people that take PPIs (proton pump inhibitors like prilosac).

Posted 7/30/2006 3:16 AM (GMT -8)

Aldo,
Excellent info about sublinguals.

Also people who take statin meds for cholesterol need to supplement with CoQ10. I take 100 mg. a day of that. My docs know all the supplements I take.

Aldo you have given some great explanations here. My fibro fog prevents me from being able to explain it was well as you do.

What I wonder is if the meds like Pepcid AC do the same thing as the PPI's and if so, I do need to get my B12 checked. The earliest I can do that is in December. But in the meantime I continue on my B12 sublinguals.

Hugs to all,
Faye
Posted 7/30/2006 4:54 AM (GMT -8)
Faye, I am not really sure about that. It is a very good question. Theoretically it seems that anything that lowers the acidity in the stomach would affect breaking down B-12, but to what extent, I don't know. I will do a bit of checking on it, and will post anything that I find. One thing that is great for us is you can't take too much B-12. You could take a whole bottle and it wouldn't harm you. You pee all out that is not needed, lol.

Did you guys know that the man that donated the money to create Duke University had a severe B-12 deficiency. He must have had an intrinsic factor deficiency which prevents B-12 from breaking down in the stomach. Anyway he developed dementia from lack of B-12. He felt guilty for having so much money that he gave a large sum to start Duke University. I read this on a site about B-12 deficiency. It can make you nuts (look at me) and destroy your peripheral nerves.

It is a very serious deal. It can affect the white matter of the brain. An mri of my brain showed that I have white matter disease, lesions from 2 strokes, and damage due to small vessel disease. I have taken the PPIs for 7-8 years and started due to ulcers and erosions in my GI track. I worked for over 6 hours straight on a reply to a post yesterday. I can't do anymore EKG work, lol.

Hope all are fine today (hello Delta),

Rj

P.S. I think the B-12 deficiency is affecting my vision. The title of this thread looks like it is B-12 "spots". I hain't got any of them yet :)

Post Edited (Aldo) : 7/30/2006 6:57:51 AM (GMT-6)

Posted 8/1/2006 3:09 PM (GMT -8)
:-)  they are b-12 dots not spots,  sorry people.  aldo, did you ever answer my question? if you put them under your tongue then they do not go directly to your stomach, so wouldn't that work?
Posted 8/11/2006 2:11 AM (GMT -8)

Aldo,

Well if B12 can make one nuts, than maybe that is my problem. lol

I've been on something like Prilosec, Axid AR, or Pepcid AC since 1990, and never knew about the B12 problem until recently.

I'm up to 5 mg. of B12 now, sublingually, a day in the early afternoon.

Dreamgirl,

I think one needs to use the formula that is specially for sublingual use. Not just use any old B12 under your tongue. It has to be absorbed by the blood vessels under your tongue. But I also feel some of it going down my throat because it is strawberry flavored. That is why I'm using 5 mg. now.

Hugs,
Faye

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