I have had an increase of PVCs and PACs lately. They even caught a burst on atrial fibrillation on an event monitor last month. I have an appointment with my cardio on Sept. 26th. I am currently on Toprol XL (50mg), but it doesn't seem to be working anymore. I have been reading about acebutolol for PVCs, and from what I've read - it really seems to reduce PVCs in most people. Is anyone on it, and how has it affected your arrythmias?