Hi there notreason...welcome to healingwell.
When it comes to drug interactions, I have a clickable link that you can go to...it is in my signature, and you can see what drugs are safe to mix and not.
You can also call your local pharmasist, or even your doctor to find out if what you are doing is safe.
You could be developing a tolerance to Prilosec...that is a possibility, and something you should talk to your doctor about
Also, you could use a liquid antacid and see if that offers any relief to you.
Please, stick with us, let us know how you are doing, and let us know if you need any other help...we are always here.
Wishing you the best!
GERD Forum Moderator
Please share, only if you can spare!
Diagnosed with Generalized Anxiety Disorder (GAD) and Panic Attacks.
Clickable Link that may be of interest to some...as I find I often like to check drug interactions...Drug Interactions