I've had GERD since October 2006. In this time of one and a half years, I have tried Prilosec (no help at all), Aciphex (a little help but still felt some burning most days), Prevacid (which helped but still had to take Zantac or Pepcid along with it most days). Now, I have been on 80 mg Nexium since April, 2007, and it worked fantastic. Didn't even realize I had Gerd until just one month ago I started refluxing again. Now, I have to take about 300mg a day of Zantac along with the Nexium just to get through the day.
So what is the longevity of these drugs? I thought they were suppose to work for years before your body would get used to them. I don't have much choice left as far as drugs go.
What experiences have any of you had with these drugs lasting or not lasting forseveral years before you need to change to another drug? Any input would be helpful as I see my GI doc tomorrow to discuss what to do.