If the Nexium was working for you I would try the Prilosec. Nexium came out only when they were going to lose their patent on Prilosec. They added one ingrediant(so to speak) so they would have a new cash cow since they were losing the other. The new ingredient was supposed to heal the esophagous. Does it? I don't know but Prevacid, Protonix and Aciphex are basically the same thing with a molecule apart. I would try the Prilosec and see how you do or you Doctor can give you a prescript
ion for the generic version and your insurance will cover it. It comes in only 20mg so you would have to take 4 a day obviously but it is cheap with prescript
ion. I get 100 for $7.00 The other PPI's are almost as expensive as Nexium. The other thought is to buy from Canada or India and save a lot of money that way if you are determined to use the Nexium. Most Doctors don't feel one is that much better than the other and like someone said each one has its own problems. Protonix made me worse. That is a very high dosage you are on. I hope you are making sure that you get enough Calcium and Vit D as studies are showing that the PPI's may cause osteoporosis. As soon as this patent runs out they will be coming up with a newer version to get your money. My Doctor calls acid relux the disease of the decade. Everyone seems to have it.