If you can elevate the head of your bed (you can get bed risers at Bed Bath and Beyond--I saw them today, or a medical supply store, or even bricks or blocks will work--the risers are more stable, though) When you are sleeping, you're laying down, and your dysfunctional LES valve allows the acid to reflux into your esophagus. If you elevate your bed, gravity will help to keep the acid in your stomach.
Using a pile of pillows isn't the same, because it can actually put pressure on your stomach by bending your body there, thus sending more acid up to your esophagus. You can also try a wedge, which is available at medical supply stores, but they still aren't as good as elevating the head of your bed. They can bother your back, too, if you slide down on them.
Whenever I have a reflux episode, I've always used Maalox. It seems to coat the stomach/esophagus nicely and give relief. Plain old water can be great, too. If you take an acid reducer med, (Prevacid, Prilosec, etc.), take it at dinnertime. Also, try not to eat within 3-4 hours before going to bed.
Good luck! We're here to help however we can!