When does Nexium begin to work?

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jc2009
New Member


Date Joined Oct 2009
Total Posts : 6
   Posted 10/11/2009 6:09 AM (GMT -7)   
Hi...
 
I know everyone reacts differently to medication, but I am wondering for those that take 40mg Nexium, how long were you taking it until you felt some relief?
 
I had a chronic cough for 5 weeks, and was diagnosed with bronchitis and ashtma.  I went for a second opinion, and the doctor now thinks it is GERD.  I've been on Nexium for 5 days now, and even though I am not coughing as much, I still feel chest pain and the occasional acidic taste in my mouth, as well as hoarsness.  I follow all the rules of what not eat it as well.  I take Tums, but it a temporary relief for me.
 
I have not had the Barium Test yet, but the doctor said this is the next step....
 
Thank you in advance for your advice....
 

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32602
   Posted 10/11/2009 9:31 AM (GMT -7)   

Hello jc,

Proton pump inhibitors will typically cause reduction of acid and improvement in symptoms of heartburn within 24 hours. If there is esophagitis present, it will take a longer period of time for symptoms to improve. If there is no improvement after a week of therapy, you should check with your doctor. It may not be that the diagnosis is incorrect, but possibly that the dose of medication may need to be increased, or a different proton pump inhibitor prescribed.

Take care and stick with us.

Kitt

 


 

Kitt,
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couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 14475
   Posted 10/11/2009 11:22 AM (GMT -7)   
Welcome!

I, too, have the chronic cough from GERD. The Nexium helped me feel better about 7 days after I began.
Other tests to be done will be the endoscopy, bravo test, and manometry test.
My cough comes from acid overflowing into my windpipe causing a mucous buildup.
It has recently gotten worse and I now face surgery. I'm planning on the EsophyX TIF procedure.

Joy

jc2009
New Member


Date Joined Oct 2009
Total Posts : 6
   Posted 10/11/2009 12:57 PM (GMT -7)   
My Gerd started with a simple cough, no cold or flu symptoms.  The cough has lasted for 5 weeks.  In that 5 week period, I hated a Cat scan of the chest, chest xray, PFT breathing test, ECHO of the heart, and all have come up negative.  For the cough, I was treated with 2 different antibiotics, with the doctors thinking it was bronchitis.  When the antibiotics did not clear up the cough, the pulmonary specialist treated me for asthma with Asmanex spray and Albuterol with a nebulizer.  These did not work.  I would still wake up with gagging, violent cough and the inability to breathe.  After she told me that I have reactive airway disease and sent me to a throat, ear and nose specialist, I decided for a second opinion.  I began taking TUMS for a week before my appointment with another pulmonary specialist.  I told him that I was feeling a little better from the TUMS, and therefore he decided to put me on 40mg per day of Nexium.  I still have the heartburn and chest pain feeling and also occasionally taste the acid in my mouth.  My rib muscles are so bruised that I can't even cough anymore without dropping to the ground.  Most of my coughs are now short little coughs as if I am clearing my throat. 
 
I also have read alot of the Apple Cider Vinegar/Honey/Warm water combination and I am willing to try to for some relief. 
 
Thanks to all for their advice...

Alcie
Veteran Member


Date Joined Oct 2009
Total Posts : 4931
   Posted 10/11/2009 4:45 PM (GMT -7)   
None of the ppi's last 24 hours.  Nexium lasts the longest, but still not all night if you take it in the morning.  It makes a big difference HOW you take it too.  The capsules we take now say delayed release.  So taking it a half hour to an hour before eating in the morning may not get enough into your system first thing.  It doesn't for me.
 
My method, not necessarily doctor approved, but from many years of trying everything:
While the coffee's brewing, I open the 40 mg capsule and dump about half into my hand.  It'll jump out of a spoon, so the hand works best.  I swallow the granules with a little water.  It's ok in the literature to open capsules and put the grains on applesauce.  Then in the evening i take the other half of the granules.  I get a bigger shot first thing when I need it and more to get me through the night.  I tried taking 2 capsules a day and had bad side effects.  I tried taking other meds in the evening (ranitidine, etc.) but they didn't get me through the night.
Alcie
 
 


couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 14475
   Posted 10/11/2009 7:10 PM (GMT -7)   
I'm on 40mg 2X a day and 300 zantac. It doesn't touch my cough.

Joy

couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 14475
   Posted 10/12/2009 6:12 AM (GMT -7)   
I follow all the doctor's rules.

1. raise head of bed
2. no food three hours before bedtime
3. don't bend over with food in stomach
4. no reclining for two hours after meals
5. take my meds faithfully
6. don't stuff yourself
7. watch your trigger foods

Despite doing all of this I still have problems.

Joy

jc2009
New Member


Date Joined Oct 2009
Total Posts : 6
   Posted 10/12/2009 9:53 AM (GMT -7)   

Thank you for all your advice... 

I am 5'3" and only weigh a buck (not the animal), and watch everything I eat.  I don't eat beef or pork, and always look for low fat or fat free foods now for over 10 years.  Food has never been an indulgence for me because I have to be careful of what I eat in order not to get a stomach ache.  But Gerd was never an issue until now.  I don't sleep in a bed, but rather my couch now since I can sleep upright more easily.  Walking is the only exercise I have to do since I have a dog.  I can't fully exercise because of the pain in my ribs which I hope will ge better with Tylenlol. 

I take Nexium at noon for the last 6 days.  I tried it at 8am and my body did not like that, so now I wait before lunch.  As someone said earlier, I am noticing that the heartburn gets worse for me around 4 or 5am as if whatever has been working throughout the day, ever so slightly, is completely wearing off at night.


Alcie
Veteran Member


Date Joined Oct 2009
Total Posts : 4931
   Posted 10/12/2009 5:24 PM (GMT -7)   
JC -
you could try splitting your Nexium dose like I do.  None of the ppi's work 24 hours.  And they all take at least a half hour to start working and need to be taken that far in advance of eating.
 
Some docs will double up your ppi to a whole dose twice a day, but I had a bad reaction to that much.
 
Lately, after some miserable Bravo testing irritated my esophagus, I have found I need to add Zantac in the afternoon.  It's not a very powerful med.  Pepcid is stronger.
 
Food triggers are often an acquired problem, as they were for me.  Fat may not have anything to do with it.  Try keeping a food journal to see if you can make a connection.  I got my reflux nearly completely under control by eliminating my triggers.  At least it worked until I had a high speed accident that shoved my stomach into my chest, for which I am now testing for surgery.
Alcie
 
 


couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 14475
   Posted 10/12/2009 6:42 PM (GMT -7)   
Skunker, I use bed risers on the head of my bed. They raise it about 8 inches. I slide to the foot every once and awhile and have to push myself up again. :))
I also sleep with a CPAP which pushes the acid down some with the pressure.

Joy
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