I Had a really bad bout of reflux 4 years ago and had an endoscopy. My consultant said that i Had GERD and would remain on PPI's for the rest of my life!! (I was only 25). When I went to see my GP about the endoscopy results she was horrified that the consultant had told me this. She said that current research on the drug showed that there may be long term complications and told me to make lifestyle changes instead. I was medication free for 4 years.
Recently I was stressed out with University finals and felt a "lump" in my throat...the reflux must have came back. I had no symptoms as I knew it but the ENT specialist said that the inflammation was definately there. She prescribed 40mg Omeprazole which in my opinion was overkill. I was on 20mg when I had bad symptoms.
I didnt feel comfortable taking the meds and about 5 days after stopping them, started to get terrible pains in my stomach. I read about Acid Rebound HyperSecretion and omeprazoles effect on gastrin and histamine production. At the time I was trying to take H2RA's but these were having no effect on the symptoms. I told myself that if this drug was having no effect then surely the problem wasnt acid related. I also had no other GERD Symptoms.
I am now pain free and on no medication. The pain disappeared overnight after causing problems for about 3-4 weeks. From what I have read, H2RA's dont work well after being on Omeprazole as the high levels of Gastrin produced after coming off the meds stimulate elevated levels of Histamine.
When the pain was at its worst I went to an NHS walk in centre and their response was to put me back on PPI's. I was horrified.
I have a background in medical science and this was what gave me the confidence to question my health care providers and come off the drugs. However it worries me that these drugs are prescribed so liberaly to the general public especially as the rebound can cause a cycle of addiction.
I have had my rant now so thanks for listening...