I was diagnosed with LPR (reflux into the throat) 3 or 4 years ago. Many treatments failed to help, but I just got a very encouraging report from my ENT and wanted to share. She noticed great improvement in the status of my throat since my check-up last winter.
It took high-end doses of meds to do it: I've been on Nexium 40 mg TWICE a day for about a year and a half plus Zantac 300 mg TWICE a day for about 9 months. That dose of Nexium is typical for LPR but not GERD, although most online sources only recommend 6 months, not 18. The total 600 mg Zantac is definitely not typical, nor is it recommended. My local docs, in fact, were very negative about that dosage.
I started taking that much Zantac by accident, but had relief within 3-4 days from the nightly gasping awake unable to breathe that had bothered me for nearly 4 years. But my first ENT was so dismayed by that dosage that he made me stop. However, when I saw an expert at a reasearch hospital this summer, he told me it was okay although at the extreme high end of okay, so I went back to it. My current ENT was also very suspicious of the dosage, but she just saw the results first-hand, and so didn't argue the point. She said to continue my current doses, by the way.
Because I've got a lot of food allergy issues, I wonder if maybe the Zantac, being an antihistamine, helped me more than it would others.
Just wanted to share something that has been successful for me in treating LPR, which is known to be pretty tricky to beat.
PS - By the way, in the beginning, I also followed all the recommended lifestyle changes to a T -- raise the head of the bed, avoid certain foods, don't eat close to bedtime, lose weight, etc. -- and they made very little difference in the choking awake problems. Not much of a surprise with LPR, though, since it only takes a tiny bit of acid to cause a big problem in the throat.