Success with LPR

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Veteran Member

Date Joined Jul 2005
Total Posts : 1952
   Posted 12/1/2010 1:46 PM (GMT -6)   
I was diagnosed with LPR (reflux into the throat) 3 or 4 years ago.  Many treatments failed to help, but I just got a very encouraging report from my ENT and wanted to share. She noticed great improvement in the status of my throat since my check-up last winter.
It took high-end doses of meds to do it: I've been on Nexium 40 mg TWICE a day for about a year and a half plus Zantac 300 mg TWICE a day for about 9 months.  That dose of Nexium is typical for LPR but not GERD, although most online sources only recommend 6 months, not 18.  The total 600 mg Zantac is definitely not typical, nor is it recommended.   My local docs, in fact, were very negative about that dosage.
I started taking that much Zantac by accident, but had relief within 3-4 days from the nightly gasping awake unable to breathe that had bothered me for nearly 4 years.  But my first ENT was so dismayed by that dosage that he made me stop.  However, when I saw an expert at a reasearch hospital this summer, he told me it was okay although at the extreme high end of okay, so I went back to it.  My current ENT was also very suspicious of the dosage, but she just saw the results first-hand, and so didn't argue the point.  She said to continue my current doses, by the way.
Because I've got a lot of food allergy issues, I wonder if maybe the Zantac, being an antihistamine, helped me more than it would others.
Just wanted to share something that has been successful for me in treating LPR, which is known to be pretty tricky to beat.
PS -   By the way, in the beginning, I also followed all the recommended lifestyle changes to a T -- raise the head of the bed, avoid certain foods, don't eat close to bedtime, lose weight, etc. -- and they made very little difference in the choking awake problems.  Not much of a surprise with LPR, though, since it only takes a tiny bit of acid to cause a big problem in the throat. 

Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 12/1/2010 5:13 PM (GMT -6)   
My reflux was called "Silent GERD". The LPR symptoms are very similar to it.
I was on 80mg of Nexium and 300 zantac for nearly two years. The doctor frowned on doing more.

Veteran Member

Date Joined Jul 2005
Total Posts : 1952
   Posted 12/1/2010 7:41 PM (GMT -6)   

I do wonder when/if we'll reach a limit. Funny, though, I think I do okay without the Nexium on those occasions when I've run out for a few days, but the Zantac has become a life-saver.


Veteran Member

Date Joined Oct 2009
Total Posts : 5029
   Posted 12/1/2010 7:53 PM (GMT -6)   
I was able to control my reflux when I eliminated my food triggers. I still needed Nexium for acid control because my LES was not very good, but my stomach quit jumping/refluxing/pushing. I had to have the surgery only when my stomach got pushed into my chest in an accident, forcing my LES to stay wide open.

I still have symptoms - stomach heaving, which triggers tachycardia - when I eat foods with sulfite above my tolerance level or with lactose, to which I am also intolerant/sensitive.

I don't have IgE reactions to foods except for sunflower seeds, although I do have dust, mold, grass and tree pollen allergies. I take shots for those. You might try the allergy shots. They don't hurt. I sometimes give them to myself - just like a diabetic, same tiny needle just under the skin in the thigh. I don't usually even feel them.

Elite Member

Date Joined Apr 2007
Total Posts : 32602
   Posted 12/2/2010 10:09 AM (GMT -6)   
Good to know your latest test showed great improvement in your status.  I know you have many allergies and you may have a point regarding the use of Zantac.
Hope things to continue to go well for you.
Moderator: Anxiety/Panic, Osteoarthritis, GERD/Heartburn and Heart/Cardiovascular Disease.

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