Just a little advice...

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New Member

Date Joined Dec 2010
Total Posts : 1
   Posted 12/18/2010 5:24 PM (GMT -6)   
Quick (boring) history...
33 year old male. 4 year history of occasional indigestion, rarely life bothering. Sorted with antacids/otc ranitidine.
Gradual worsening of symptoms about 6 months ago.
Went to dr's. Got lansoprazole 30mg daily.
Went back a week later. Insisted on stool test.
H.pylori positive. Metronidazole/amoxicillin for a week.
Started feeling constantly nauseas during this.
Constant burping/chest pressure/food taking ages to go down.
Went back. Insisted on endoscopy.
Had it last week. After spending weeks convincing myself I was definitely dying.
Had it awake. A bit unpleasant but over quickly.
Report was: oesophagus normal, stomach - mild antral gastritis, duodenum normal. H.pylori now negative.
My symptoms continue although more manageable now and my abdo pain has pretty much gone.
Sorry for going on!....

My question is, will this likely be it for ever now?
I have already tried stopping the ppi but I was in pain within two days (i've read this is common).
Does 30mg of Lasoprazole sound like a large dose to be having?
My digestion is still very slow. I'm presuming this is down to my eating habits. I'm still eating in a similar way to before I was ill.
i.e. Too much, too fast and too often.
Are worsening of symptoms also linked to anxiety disorders? Something i've suffered with for years.
Sorry for going on...

I know I need to get back to my docs.
You always get the impression you're wasting their time.

Many thanks.

New Member

Date Joined Dec 2010
Total Posts : 7
   Posted 12/18/2010 6:56 PM (GMT -6)   
Do a Google search on stopping PPIs or acid rebound and you'll find a lot of info on acid rebound syndrome and how to wean down off the medicine gradually. I am currently dealing with acid rebound caused by going cold turkey off of Prevacid. I had bad side effects and had to stop taking it. I'm now doing Zantac for a few weeks to get me through the rebound and then I'll wean down off of that gradually. The problem with going off the PPI is that they have suppressed your acid-producing pumps in your stomach and in response, your body produced more gastrin (the hormone that controls acid production) trying to "fix" the lowered acid. This isn't a problem while you are still suppressing the acid production with the medication, but when you stop your body begins to hypersecrete acid in response to the elevated gastrin levels. This seems to take at least 2 to 4 weeks to improve. I've been off my Prevacid for 2 weeks now and I was in horrible abdominal pain with the extra acid until I started the Zantac today.

You should do some investigation into acid reflux diets, as well. If you want to stay medication-free, then you need to change your lifestyle. Eating smaller, more frequent meals and avoid eating within 3 hours of bedtime. Avoiding fried foods, citrus, tomatoes, chocolate, alcohol, caffeine, sodas, teas (except for herbal), spicy foods, and processed carbohydrates seem to be the way to go for those who have severe acid reflux. Once you've got things under control off medication, you can begin to try some foods to see if they are "trigger" foods for you, if not, you can add them back into your regular diet. You may be one of the fortunate ones who only need to avoid fatty and spicy food. Losing weight can help, if you're a bit overweight. Smoking is also a no-no.

Hope this helps!

Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 12/18/2010 10:16 PM (GMT -6)   
Go slow in your weaning and it won't be as bad. I took a full month to go every other day, then every three days, then every four days, etc.
By day four you do hit rebound but it lasts only a couple of hours.
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