Does everybody get acid rebound when stopping PPIs??????

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New Member

Date Joined Dec 2010
Total Posts : 12
   Posted 3/28/2011 11:39 AM (GMT -6)   
I have been on 40mg omperazole for three months straight, and I just felt like I couldn't deal with how bad the medication was making me feel. I have stopped taking it. Today is my 3rd day without it. I am trying to manage all my symptoms with Zantac now.

I was wondering, does everyone get the "acid rebound" effect when stopping PPIs???

I'd like to hear your experiences. I figured after three months, I would be having some immediate rebound, but I haven't experienced it yet. Maybe my body is just slowly pushing out the stored PPI remaining in my system???

Regular Member

Date Joined Feb 2011
Total Posts : 24
   Posted 3/28/2011 12:50 PM (GMT -6)   
I'm off Nexium for about 3 weeks now after taking it for a month, and I can't say I had any rebound acid, and if i did it was very minimal I could hardly feel it.

Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 3/28/2011 4:30 PM (GMT -6)   
I was on it for about ten years and the rebound hit me at day four.

New Member

Date Joined Mar 2011
Total Posts : 3
   Posted 3/29/2011 12:48 PM (GMT -6)   
weneva i stop my ppis , i get tremendous rebounds, i have been on dem for over six years and one day widout dem means a hell lot of suffering for me

mock turtle
Regular Member

Date Joined Mar 2011
Total Posts : 467
   Posted 4/1/2011 10:59 PM (GMT -6)   
i switch between a PPI (omeprazole) and an H2 (ranidtidine) every two weeks in an attempt to avoid rebound. i dont know if this is an effective strategy. after 3 months of this i took a week off and tried to manage with just antacids I had reflux during that week and some burning but no worse than before the days of PPIs. so far i have not experienced really bad rebound. but i can not prove that flipping back and forth is effective.
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