My doctor switched me from Dexilant 60mg (1/day) to Zantac 300 (1/day). His reason was that my symptoms are under control with Dexilant, a PPI, so he wanted to see how I would do with Zantac, an lower-potency H2 blocker.
I'm confused about why I would take Zantac 300 once a day vs Zantac 150 twice a day. The Dexilant was time-released; thus, one pill a day provided the equivalent of two doses in 24 hours.
But the Zantac is not time released, and I've read that it's effective for 6-8 hours. So, if I take the Zantac at 9:00 at night, it should be ineffective during the day, right?
Also, I've read that the stomach goes through "gastric emptying" every couple of hours and recreates stomach acid in each cycle. If that's right, then what effect could Zantac 300 possibly have during the hours of, say, 9:00 AM to 9:00 PM?