I've taken what seems to be nearly every type of mainstream GERD medication out there. Ranitidine, omeprazole, pantoprazole, and finally Aciphex. Aciphex was by far the most effective medication, and kept my GERD symptoms under control for the most part. Unfortunately, I am no longer able to get them through the Veterans Affairs at no cost. I tried using the prescription at Walgreens but there is no way I can afford a 90 day supply for nearly $500. So I went back to omeprazole. Which brings me to my current situation.
Omeprazole was what I was using prior to discovering Aciphex. It seems to not be nearly as effective as it used to be. I take 20mg twice per day before meals, and take 150mg of ranitidine twice per day as I feel symptoms arise. This combination was recommended to me by my GI doctor. Unfortunately, it isn't enough. I still feel GERD symptoms, usually at night. I'm afraid to up my dose and it's a pain to get a hold of my doc. I should really switch to the private side, VA doctors/nurses are sometimes impossible to work with.
One interesting thing to note is that while taking Aciphex and though I felt little to no symptoms, a endoscopy revealed inflammation of the stomach lining (no surprise I guess). So although it was helping with the pain, it wasn't really attacking the root cause?
What has or has not worked for you? I'm thinking about switching to another med, possibly lansoprazole (Prevacid).