No relief in sight...

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New Member

Date Joined May 2011
Total Posts : 2
   Posted 5/13/2011 8:46 PM (GMT -6)   
I've taken what seems to be nearly every type of mainstream GERD medication out there. Ranitidine, omeprazole, pantoprazole, and finally Aciphex. Aciphex was by far the most effective medication, and kept my GERD symptoms under control for the most part. Unfortunately, I am no longer able to get them through the Veterans Affairs at no cost. I tried using the prescription at Walgreens but there is no way I can afford a 90 day supply for nearly $500. So I went back to omeprazole. Which brings me to my current situation.

Omeprazole was what I was using prior to discovering Aciphex. It seems to not be nearly as effective as it used to be. I take 20mg twice per day before meals, and take 150mg of ranitidine twice per day as I feel symptoms arise. This combination was recommended to me by my GI doctor. Unfortunately, it isn't enough. I still feel GERD symptoms, usually at night. I'm afraid to up my dose and it's a pain to get a hold of my doc. I should really switch to the private side, VA doctors/nurses are sometimes impossible to work with.

One interesting thing to note is that while taking Aciphex and though I felt little to no symptoms, a endoscopy revealed inflammation of the stomach lining (no surprise I guess). So although it was helping with the pain, it wasn't really attacking the root cause?

What has or has not worked for you? I'm thinking about switching to another med, possibly lansoprazole (Prevacid).

Veteran Member

Date Joined Apr 2011
Total Posts : 1604
   Posted 5/14/2011 3:00 AM (GMT -6)   
I found omeprazole effective but with some side effects, but my reaction to them is not common. They didn't help my stomach immediately; took 3 months to get stable. I also had gastritis whilst on them and signs of reflux, but symptom wise they had it about 80% covered. I can only take ranitidine now and it just doesn't do the job, even on high dose. I'm not bad enough for surgery or any other treatment (I'm told) so I just have to put up with it, which I'm not happy about, especially as I'm concerned about acid damage to my oesophagus.

New Member

Date Joined May 2011
Total Posts : 2
   Posted 5/14/2011 7:23 AM (GMT -6)   
I took omeprazole for about 4 years with no healing effect whatsoever. I think it actually got worse over that time period. I used to be able to take 1 and be fine for the most part. Now 2 doesn't even do the trick.

My GI doc said her main concern was the increased chance of stomach cancer with the constant inflammation. Wasn't very comforting words when I learned none of the medication I'm taking is taking care of that.

Forum Moderator

Date Joined Feb 2009
Total Posts : 7188
   Posted 5/14/2011 7:49 AM (GMT -6)   
Hi solution,
Welcome to Healing Well! I am no doctor, but I can tell you what my dosage has been over the years and you can draw your own conclusions.

I started out probably 15 years ago, like you, with 20mg Prilosec. That worked for a while, and then I was stepped up to 20mg twice a day. That was changed to 40mg twice a day. (I was not one of those people who could take PPI's without breakthrough). When Nexium came out, I was switched to that at 40mg twice a day. I was on that until gastritis/GERD (caused by an antibiotic--I have a very reactive stomach) put me into the hospital for asthma that was uncontrollable. At that point I was put on 40mg Protonix twice a day.

Ranitidine was added at 300mg at bedtime in addition to the rest.

Do you have the head of your bed elevated? Bedtime is the worst culprit for reflux, as it can just flow up the esophagus without fighting gravity.

I'm sorry to hear you can no longer get Axiphed. Hopefully they will change their mind and offer it again in the future.

I ended up getting the Nissen Fundoplication surgery--not because my reflux was so out of control (I was never one of those with acid and food traveling up my esophagus), but the reflux I did have was causing havoc with my lungs.

Good luck! I'm sure others will be by to share their experience and ideas.
Take care,

Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 5/14/2011 8:21 AM (GMT -6)   
I started with the usual tums, then nexuim once a day, then twice a day, then added 300mg of zocor at bedtime. When it stopped working I had the surgery. Now I have no trouble with reflux.
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