Hexylresorcinol lozenges for LPR

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Chuck T
Regular Member

Date Joined May 2011
Total Posts : 143
   Posted 5/16/2011 12:21 PM (GMT -6)   

Hi, Im a new poster on the Board, but have been reading it for several weeks. I was recently diagnosed with LPR and Gastritis (and think im starting to get some symptoms of classic GERD too). The weird thing is that all my symptoms seem to be worse on PPIs (dexilant 60mg). I started with a lump in my throat that wouldnt go away for a month, got on PPIs, and it turned into painful throat burn and then Gastritis. I dont know if I was always going to progress to where I am now, or if the PPIs played some part in it.


Anyways, as im sure many of you did when you were first diagnosed, I have been looking on the internet for information about my ailment. I recently read an article by Dr. Koufman that indicates that Pepsin is the main culprit in reflux damage. I also read that Hexylresorcinol is an anti-pepsin agent, and can be found in some cough drops. Has anyone on this board used Hexylresorcinol lozenges and gotten relief from LPR? Im thinking about giving it a try, but I think you have to order them online and I dont want to waste my time if they arent going to work. Right now, gargling with baking soda water a few times a day is helping, but I think the lozenges could be a huge help too.

mock turtle
Regular Member

Date Joined Mar 2011
Total Posts : 467
   Posted 5/16/2011 3:38 PM (GMT -6)   
i commented about hexylresorcinol posing similar questions, on a thread here at healingwell , maybe about 6 weeks ago. i had seen some reference on the internet , like you did, that hexylresorcinol neutralizes pepsin.

i queried several doctors and never didi get a satisfactory response. i did find that several readily available cough drops that have the words lemon and honey, all evidently manufactured by the same people for different retailers, have as an unlisted ingredient, hexylresorcinol. yes i know that doesnt make sense.

i even wrote the venerable dr kauffman an email but did not hear back on the issue. i believe halls and safeway brands were alleged to have the ingredient unlisted , but i read sucrets do too

i tried some and it seemed to help but i cant prove it was the hexylresorcinol that did it or was even for sure an ingredient.

i have been battling back from the edge with LPR and can recommend several very effective strategies

eat very small meals ( no more than the volume of food than what can fit in your cupped hands

no chocolate no cigarettes no alcohol... all three greatly weaken the les (lower esophageal sphincter).

eat very small meals

sleep with your bed inclined at least 10 inches at the head elevating bed or using a wedge...pillows alone dont work cause they induce a bend at your torso mid section that puts pressure on your stomach

eat very small meals

dont eat after 6 pm ,nothing, not even a nibble and never bend over or lay down flat after eating ( wait 2 hours)

eat small meals

avoid fatty foods, greasy foods and limit your consumption of meat, it takes longer to digest

loose weight if you are at all over weight...much research has shown this is a major factor in adult onset gerd and lpr

eat small meals

keep a record of foods that work for you an a record of foods that aggravate your reflux , there are significant differences between people on this.... check out the many lists to be found on the internet of safe and reflux prone foods and start with that,...testing each food, one at a time for yourself

avoid stuff in cans and jars ... eat only whole foods... chemicals and preservatives are very bad for gerd - lpr

eat small meals...i eat 5 tiny meals a day and have gone from inhaling my reflux several times a week to going 5 or six days without a major reflux event, ...and yes... i quit proton pump inhibitors

ppi s helped at first and im not against them, but get off of them if.,, or when,,, you can with doctors advice and consent

it took 6 months for me to improve substantially with lots of pain and fear, and a lump in my throat along the way

best of good luck to you!

edit to correct bad spelling

Post Edited (mock turtle) : 5/16/2011 2:56:54 PM (GMT-6)

Forum Moderator

Date Joined Feb 2009
Total Posts : 7188
   Posted 5/16/2011 3:52 PM (GMT -6)   
Hi Chuck,
Welcome to Healing Well! It looks like Mock Turtle has offered you some excellent advice. I would add one thing. Stay away from rough food, as your stomach is inflamed, and foods that are not smooth will further irritate your stomach lining during the digestive process, when it contracts and mashes whatever you've eaten.

Also, elevate the head of your bed, so gravity can help acid where it belongs, rather than migrating up your esophagus. You can put blocks or risers under the legs at the head of the bed...using extra pillows only causes more acid to be forced into your esophagus, as it puts pressure on your stomach.

Good luck getting things straightened around,

Chuck T
Regular Member

Date Joined May 2011
Total Posts : 143
   Posted 5/17/2011 11:52 AM (GMT -6)   
Thanks guys, those are some great tips. Unfortunately, the small meals thing isnt really something I can do right now because the doc has me on carafate for my gastritis. Have to drink it 2 hours after eating, and cant drink it less than an hour before eating. So im back on 3 meals a day until I can get this gastritis under control.
Do you think that a 9" tall 36" long wedge pillow will work? Right now I have one that is 6" tall and 24" long and dont really like it too much.
I think im going to try and order some of the losengers containing hexylresorcinol as an active ingrediant. Ill keep the Board posted on how it goes.
Mock, im really sorry to hear about your recent health issue. I will keep you in my prayers!
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