New study says patients who can't tolerate PPIs may benefit from SSRIs.

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Veteran Member

Date Joined Oct 2009
Total Posts : 4970
   Posted 6/20/2011 5:10 PM (GMT -6)   
In an article reported on in Reuters (I read it in Medscape) it was noted that some patients with NERD (non-erosive reflux disease) with typical reflux symptoms have hypersensitive esophagus.  Citalopram (Celexa), an antidepressant was effective vs placebo in relieving GERD symptoms in the small study.

Veteran Member

Date Joined Apr 2011
Total Posts : 1604
   Posted 6/22/2011 9:57 AM (GMT -6)   
Thanks for this info
When you read through it looks like they mean patients for whom ppis do not work, rather than patients who cannot tolerate the ppi drugs, but it is interesting. I have wondered whether the constant acid reflux means we all have some hypersensitivity of the oesophagus. The article also made me wonder if St John's Wort would help some people, but I'm not sure about taking it alongside ppis. The herb can cause sun sensitivity, as do ppis, so possibly not a good idea to combine that particular side effect. If I ever get properly off ppis I might try St John's Wort!
New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma
New Topic Post Reply Printable Version
Forum Information
Currently it is Friday, March 23, 2018 7:01 PM (GMT -6)
There are a total of 2,943,295 posts in 322,941 threads.
View Active Threads

Who's Online
This forum has 161308 registered members. Please welcome our newest member, TNLymeGirl.
371 Guest(s), 8 Registered Member(s) are currently online.  Details
Break60, sandyfeet, The Dude Abides, Girlie, magoo2, Saipan Paradise, k07, suchatravesty