PPI and carafate

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stkitt
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Date Joined Apr 2007
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   Posted 6/30/2011 7:15 AM (GMT -6)   
If you take sucralfate (Carafate), avoid taking it at the same time you take your PPI medication . Sucralfate can make it harder for your body to absorb PPIs. Wait at least 30 minutes after taking this medicine before you take sucralfate.
 
Any comments or info on the above statement to help clarify for our members who take both of these medications.
 
Thanks to all who take the time to leave a comment.
 
Kindly,
Kitt
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Jeronimo
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Date Joined Apr 2011
Total Posts : 76
   Posted 6/30/2011 8:00 AM (GMT -6)   
When I take my PPI (pantoprazole), I wait at least 1 hour before eating, thats what the prescription says.

sewfun
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Date Joined May 2011
Total Posts : 146
   Posted 6/30/2011 9:23 AM (GMT -6)   
My PCP wanted me to take my PPI, wait 1 hour then take the Carafate, wait 30 minutes and then eat. I found even that to make the PPI less effective. It also interfered with my appetite. So I now only take the Carafate at bedtime and an hour before lunch. That keeps it completely away from all meds.

According to the paperwork with my prescription, Carafate should not be taken within 2 hours, before or after, any other medication because of the absorption issues. The only exception is antacid, then it recommends 30 minutes.

I'd like to know if eating after an hour of taking the Carafate means the Carafate loses it effectiveness or does it still continue to work?

Sewfun

Post Edited (sewfun) : 6/30/2011 9:30:43 AM (GMT-6)


mudmagnetmum
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Date Joined Apr 2011
Total Posts : 1604
   Posted 6/30/2011 1:39 PM (GMT -6)   
There's some recent research saying Carafate also reduces the availability of thyroxine too. Anyone taking thyroxine, epilim or warfarin should also be very careful I think!
New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma

dencha
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Date Joined Feb 2009
Total Posts : 7181
   Posted 6/30/2011 6:45 PM (GMT -6)   
The package says to wait two hours before or two hours after taking any kind of medication.

I questioned these directions with a pharmacist and she said that generally any medication you take will not take a full two hours to empty out of yoru stomach, so you can play with that number a bit more...perhaps take the med and wait an hour/fifteen or an hour and a half before taking Carafate.

She said that it was really important to take the Carafate the full two hours before meds, though. Otherwise the medications you take will not be absorbed properly.

Also, I believe you need an hour in between Carafate and antacids like Maalox.

I have taken Carafate as needed for years and have experienced no side effects. My family doctor said that it was good Carafate worked for me, because it is a very benign drug, and pretty much passes out through the GI tract without much of anything being absorbed.

I have a reactive stomach, and I really appreciate the long lasting coat of protection that Carafate Suspension puts on my wrap and stomach when they're irritated. I never want to be without it, just in case! turn

Denise

mudmagnetmum
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Date Joined Apr 2011
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   Posted 7/1/2011 3:34 AM (GMT -6)   
Hi Denise, I wouldn't mind trying carafate but it's just not used here in the uk. My point with other drugs is that some medications need to remain at a constant level e.g. Blood thinners and epilepsy medicine and so on. So if for example you are on drugs for epilepsy and then have a GERD flare up and suddenly take carafate, or randomly increase what you normally use, then you risk a sudden variation in your blood levels of your other drugs. Same goes for heart medication and diabetes drugs; you can't risk random variations in the available levels as there could be disastrous consequences!
Glad it works for you though!
MMM
New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma

dencha
Forum Moderator


Date Joined Feb 2009
Total Posts : 7181
   Posted 7/1/2011 7:01 AM (GMT -6)   
Hi mudmagnet,

I have never read that Carafate (perhaps you have it in the UK as sucralfate?) interacts with other drugs unless you take them at the same time. From my reading/experience, as long as you take Carafate 2 hours before or after other medications it does not interfere with other drug uptakes, or change them in any way.

Here are some links for you to check out, if you haven't already:
www.drugs.com/mtm/carafate.html

www.medicinenet.com/sucralfate-oral/article.htm

www.webmd.com/drugs/mono-68-SUCRALFATE+TABLET+-+ORAL.aspx?drugid=14156&drugname=Carafate+Oral

Hope you're having a good day!
Denise
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