Future lab grown LES valve?

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Regular Member

Date Joined Oct 2009
Total Posts : 175
   Posted 8/10/2011 2:56 PM (GMT -6)   
I read an article that researchers have grown the first artificial functional sphincter muscle from human cells in a laboratory. It has working nerves to control it, and they were able to transplant it into mice where it continued to function, and blood vessels formed to feed it like a normal body part. They are working on the lower digestive tract sphincters, but it seems like this technique could also be used to replace the lower esophageal sphincter to cure GERD.

I'm sure this is years away from being implantable into humans as a replacement valve, but it's encouraging that advances like this are being made. I for one would love to get a brand new working replacement LES valve someday. An advancement like that would make fundoplication obsolete.

Here's a link to the article:


Veteran Member

Date Joined Jul 2011
Total Posts : 656
   Posted 8/10/2011 3:02 PM (GMT -6)   
Absolutely amazing. Thank you for sharing!

Elite Member

Date Joined Apr 2007
Total Posts : 32602
   Posted 8/10/2011 5:51 PM (GMT -6)   
Interesting article.  Thanks for sharing.
Moderator: Anxiety/Panic, Osteoarthritis, GERD/Heartburn and Heart/Cardiovascular Disease.

"If you can't change the world, change your world"

Regular Member

Date Joined Jun 2011
Total Posts : 96
   Posted 8/11/2011 12:59 PM (GMT -6)   
Very cool!

Regular Member

Date Joined Apr 2011
Total Posts : 76
   Posted 8/11/2011 9:13 PM (GMT 0)   
Wow! Nice! This would be fantastic with GERD and LPR sufferers!

Regular Member

Date Joined Jul 2011
Total Posts : 77
   Posted 8/16/2011 10:26 PM (GMT -6)   
future medication rocks.. :)

Veteran Member

Date Joined Jul 2011
Total Posts : 656
   Posted 8/17/2011 9:51 AM (GMT -6)   
Apparently I'm addicted to FB, as I just tried to 'like' this post and was confused when I couldn't find the button! Oops.
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