research indicates a genetic predisposition to acquiring barrets esophagus
heres an article
"Gene Mutations Linked to Barrett's Esophagus
By Nancy Walsh, Staff Writer, MedPage Today
Published: July 27, 2011
Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner
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Germline mutations in three genes appear to be associated with the development of esophageal disease, researchers reported.
Specific mutations in MSR1, ASCC1, and CTHRC1 all were linked with Barrett's esophagus and esophageal adenocarcinoma (P<0.001), according to Charis Eng, MD, PhD, of the Cleveland Clinic, and colleagues.
The most common mutation was found in MSR1 (c.877C>T, p.R293X), and was present in eight of 116 patients with the two conditions, for a proportion of 0.069 (95% CI 0.030 to 0.130, P<0.001), the researchers reported in the July 27 issue of the Journal of the American Medical Association."
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