I wish that FDA warning were more strongly worded: “Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses,” said Joyce Korvick, M.D., deputy director for safety in FDA’s Division of Gastroenterology Products. “Because these products are used by a great number of people, it’s important for the public to be aware of this possible increased risk and, when prescribing proton pump inhibitors, health care professionals should consider whether a lower dose or shorter duration of therapy would adequately treat the patient's condition.”
MY GI doc brushed it off when I brought it up. "We are just suspicious", he said. "You need to keep taking your medicine". I was on Prilosec for three months, now Nexium for two months. Next month I plan to alternate my PPI with Gaviscon. He implied I couldn't "afford" to do that, but I believe he was holding the cancer threat over my head. The threat of cancer is way less than the bone fracture, though, and I choose to lessen my risk of fractures in this manner. I already have orthopedic and neurologic problems, and making them worse WILL make my life more miserable.
Calcium is absorbed most effectively taken in two daily doses, with food. I need to check into those other supplments.