Have any of you who take PPIs made any changes based on the FDA warning about
studies that show increased bone fractures related to high dose or long-term use of these drugs?
I take 20 mg Omeprazole daily for Laryngopharyngeal reflux. I have all the classic symptoms for LPR if I don't take a PPI, so what I plan to do at my next physical exam is ask the physician to measure calcium and magnesium level and Vitamin B12 level, since these are poorly absorbed in the absence of stomach acid. I also think I should get a bone density DEXA scan, even though I'm male (age 62), because of the increased fracture risk.
I take a calcium (1000 mg)/magnesium (400 mg)/Zn (30 mg) supplement at bedtime, which should help boost these and also is purported to help with relaxation and sleep.