How long did it take your ppi to work it's best

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Veteran Member

Date Joined Sep 2011
Total Posts : 620
   Posted 9/15/2011 8:57 PM (GMT -6)   
I've bouncing offf and on meds for 2 months but finally am going to stick to one...Prevacid 30mg 4x a day as instructed by my GI to ensure it is reflux and not something else... Thanks guys

Veteran Member

Date Joined Apr 2011
Total Posts : 1604
   Posted 9/16/2011 3:16 AM (GMT -6)   
I've been on and off drugs a few times. I would say less pain after one week, but up to a month to get to maximum symptom control (which in my case is not 100% relief). However, I also have gastritis and I don't think the drugs do much for that; maybe for reflux without gastritis the benefits kick in quicker?

New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma

Chuck T
Regular Member

Date Joined May 2011
Total Posts : 143
   Posted 9/16/2011 9:25 AM (GMT -6)   
I have never heard of a dose that high. Has your GI perscribed that much to other patients? Healing time is very individual, but can take several months.

Veteran Member

Date Joined Oct 2009
Total Posts : 5004
   Posted 9/16/2011 9:39 AM (GMT -6)   
I never had much luck with Prevacid. Nexium works better on my tummy. Nexium works longer than the other PPIs I tried. Even "24-hour" didn't make any difference. I think the dose was just time-released and less was available when I needed it most - before breakfast.

Timing is critical! I only get relief if I take it 1/2 hour before eating breakfast. And it's extremely important to eat a light breakfast! The stomach's acid pumps are not available to be turned off if you don't eat something.

I've never had your dose, but I did need it twice a day just before Nissen (Toupet) surgery. The second dose didn't really help much.

I always could tell the first dose helped. The second and third day there was major relief in the morning. Just before getting surgery - giant PEH - stomach stuck in chest with valve wide open - there was only partial relief. Going through months of testing was awful.
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