What PPI are you on??

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Regular Member

Date Joined May 2011
Total Posts : 127
   Posted 9/28/2011 11:31 AM (GMT -6)   
Hi fellow GERDers,
I'm just curious which PPI has been effective for you?  I am currently taking Prevacid 30 mg first thing in the morning 30 min prior to eating.  It was immediately 100% effective but since the second day of being on it, I've had about 80-90% symptom relief overall and I'm wondering if it would be worth trying another PPI. My insurance ONLY covers Protonix so I would have to pay out of pocket for the others. I am going to try Prilosec OTC this weekend to see if it provides any additional relief. 
Do you think 80% symptom relief is pretty good as PPI's go? Just don't know if I can / should hope for more or if this means it will eventually stop working at all seeing as how it's not 100% effective.
Third, do PPI's reach their maximum effectiveness after several days or should I wait a month or more for more / complete relief?
Thanks guys,

Veteran Member

Date Joined Apr 2011
Total Posts : 1604
   Posted 9/28/2011 11:42 AM (GMT -6)   
I have tried omeprazole (which gave more side effects than others), pantoprazole and Lansoprazole. I am currently on Lansoprazole and it sort of keeps me ok but on no ppi have I ever had 100% symptom relief - they just serve the purpose of keeping the acid out of the reflux! I also have gastritis and I don't think ppis have ever helped that much with that.

I stay on the ppi because I become anaemic off them. I wish I could get off them; I don't think I'll ever reconcile myself to having to block the body's natural digestive abilities!!

My symptom control varies - if I get a flare up then it seems like the ppi is barely doing anything. Other times I can feel so good I wonder if I need less of it . . . but that doesn't happen often!

New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma

Chuck T
Regular Member

Date Joined May 2011
Total Posts : 143
   Posted 9/28/2011 2:22 PM (GMT -6)   
80% relief isnt bad. I think its a good idea to try Omeprazole since its OTC. Its basically the same a Nexium, just lower dose. Prevacid and Dexilant are basically the same too. You could also try taking 2 prevacids. But you might be able to get away with 1 prevacid and modifying your diet. I try and stay away from acidic foods, fatty foods, and gluten.

Veteran Member

Date Joined Dec 2008
Total Posts : 4961
   Posted 9/29/2011 12:19 AM (GMT -6)   
Prevacid is otc as well as prilosec. I did much better with prevacid than prilosec. I have tried both these and aciphex, and nexium. Prevacid and aciphex worked best for me. I currently am off all PPIs and don't miss them.

Take care,
Moderator: GERD/Heartburn
Nissen 6/06 and 5/09
#3 on 8/24/11

Regular Member

Date Joined Jul 2011
Total Posts : 363
   Posted 9/29/2011 1:10 PM (GMT -6)   
Hi Liz - my surgeon wanted me off PPIs and I tried. I couldn't hack it due to the gastritis and the fact that Dexilant has been the only PPI that I could ever tell really helped me much.

I used Nexium at first about 10 years ago when the reflux started and I think it helped some because the reflux had not gotten overly problematic at that point. When it did become really bad Nexium was like candy for me.

I'm back on Dexilant after surgery for GERD due to gastritis and am having an EGD next week to confirm whats going on.

Good luck and hang in there.

Falling down is part of life, getting back up is living. -Unknown

Lap Nissen Fundoplication August 1, 2011
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