Do you gain weight while taking PPI?

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Regular Member

Date Joined Sep 2011
Total Posts : 273
   Posted 11/11/2011 5:09 AM (GMT -6)   
I have heard people said it is easier to gain weight while taking PPI. It sounds counter-intuitive to me, because without the acid how do one absorb the nutrients in food.

Just want to find out. Do you gain weight while taking PPI? Weight is an issue to me because I am underweight, I am struggling to control the weight loss.

Veteran Member

Date Joined Jun 2011
Total Posts : 795
   Posted 11/11/2011 5:46 AM (GMT -6)   
I have lost weight since I developed GERD. The gastritis and esophagitis made it uncomfortable to eat at times. I don't eat after 6:00 p.m. I avoid fats in foods as much as possible. Whe I do eat, I can't eat too much at a time. These all add up to fewer calories. For me, it is the illness, not the medication.

That said, there was someone here who had a thread going about weight gain on Nexium. You could go back a few pages and see what it says.

Forum Moderator

Date Joined Feb 2009
Total Posts : 7180
   Posted 11/11/2011 10:47 AM (GMT -6)   
I don't think it made a difference one way or the other... turn It was more a factor of how much I ate!  You are likely to gain weight if your GERD has caused enough problems to create eating issues.  Once things get regulated with the acid control, you will be able to eat a better diet, and your weight is likely to increase if that's your aim.
Best Wishes,

Veteran Member

Date Joined Jul 2011
Total Posts : 656
   Posted 11/11/2011 1:45 PM (GMT -6)   
Hey WJF,

I've lost and am still losing weight on 40mg/Nexium a day, but that's because I didn't feel like eating for a solid month and now I can't eat too much without reflux. You might want to see your doctor if you're concerned about weighing too much.

Be well,
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