PPIs and constipation

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Regular Member

Date Joined Nov 2011
Total Posts : 136
   Posted 12/5/2011 12:00 PM (GMT -7)   
I have another troubling side effect of Omeprazole and that's constipation.

It can take days before i go to toilet, normal for me is one time each morning as usual.

How do you deal with constipation affected by PPIs?

Veteran Member

Date Joined Apr 2011
Total Posts : 1604
   Posted 12/5/2011 2:29 PM (GMT -7)   
That's not a side effect I've ever had - in fact I had the opposite problem when I first started taking them. Have you tried licorice (DGL)? It can be helpful for some people with GERD, but it's also a mild laxative, so it might be worth a try.

Have you been given any advice regarding fibre intake - you may need to change your diet. Try eating less wheat if you can - the very high gluten content of commercial bread can make some people constipated. Stewed fruit may help too - apples, pears, plums, prunes etc (if you can tolerate them). Syrup of figs (like Califig) is good as a temporary solution.

If you can't resolve this issue within a couple of weeks do go back to your PCP/GP - may be worth trying a different ppi. And, of course, if it lingers, you would need to be sure it is purely a drug side effect and you might need to prove that by taking a short break from the drug. Otherwise you're going to end up with investigations to check your colon etc is OK!

If it was something that occasionally troubled you before, it may be worth another visit to your doctor to get things like thyroid function checked.

Hope it settles soon - some problems do sort themselves out once you've been on the drug a little while.

New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma

Regular Member

Date Joined Nov 2011
Total Posts : 136
   Posted 12/5/2011 3:46 PM (GMT -7)   
With Nexium my stomach was normal going every day, but with all meds containing Omeprazole i get constipation.

I have in the past taken prune to drink concentrated and it helps but i can't take too much and not too often as it upset the stomach

Regular Member

Date Joined Dec 2011
Total Posts : 93
   Posted 12/5/2011 5:53 PM (GMT -7)   
I too have the opposite problem since starting the PPIs. Something that has helped me in the past with constipation is milk of magnesia--works great and no stomach cramps!

Regular Member

Date Joined Nov 2011
Total Posts : 148
   Posted 12/6/2011 8:17 PM (GMT -7)   
Try Metmucil and Rasberries for constipation.
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