Why do we experience different LPR symptoms?

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Faith224
Regular Member


Date Joined Sep 2011
Total Posts : 299
   Posted 12/15/2011 12:35 PM (GMT -6)   
Hey Guys,

Just wondering why we all get different LPR symptoms? How come some of us get hoarseness and others don't? Does it depend on the area of the throat that gets affected? Also, a typical complication of LPR is erythema of the artyenoids(wing-like structures attached to the vocal cords). I find it interesting that the reflux could affect both sides of these structures since I assume reflux passes through the middle of the throat. Any thoughts on this?

Could someone with PND not related to reflux have the same inflammation in that area of the throat? I have been on PPI's for months and have seen a reduction in my symptoms, but not in my sinuses or PND. Also, my ENT told me he sees no acid damage in sinus cavities either.


Any thoughts and/or similar experiences?

bcfromfl
Regular Member


Date Joined Nov 2011
Total Posts : 417
   Posted 12/15/2011 1:11 PM (GMT -6)   
I, too, think about this a lot, but more with respect to "...why me???"  There are many individual variances between folks, and how they respond to different factors.  Myself, I've never eaten exceptional amounts of any trigger foods, have been vegetarian for nearly 30 years, don't drink coffee, tea, soda, or smoke...yet I still came down with GERD/LPR.
 
More to your specific question, it's possible that, aside from the severity and sheer quantity of reflux reaching the throat, much of how it affects individuals could be related to sleeping habits.  If someone is more prone to sleeping on their side or stomach, then, the main quantity of reflux will be directed towards the vocal cords and bronchial tubes.  If they sleep on their back mostly, then perhaps the symptoms could be more dysphagia, burning in the back of the throat, getting in eustachian tubes, sinuses, etc.
 
Also, there could be individual variances on how the upper pharyngeal muscles are shaped, and clamp down, which directs the reflux differently.  Or, individual tendencies and susceptibilities to acid to begin with...thinner tissues, less mucous, etc.  Women have smaller voice boxes than men, thinner vocal cords, etc.
 
It's common for those with LPR to also have NERD, or no visible sign of erosions, etc.  Another factor with those who suffer from LPR is that the acid can aerosolize and travel as a vapor into the throat and lungs.  I assume that the same can happen with non-acid components, which is why it's also not unusual for those with LPR to have limited benefit from PPIs or H2 blockers.
 
Consider how headaches affect different people: some have "tension" headaches, "clusters", sinus, etc.  Pain mostly in forehead, top of head, back of head, etc.  We're all just put together differently...
 
-Bruce

Faith224
Regular Member


Date Joined Sep 2011
Total Posts : 299
   Posted 12/15/2011 2:09 PM (GMT -6)   
Hey Bruce,

Good point. I myself am a side sleeper and have lovely symptoms of dry cough, throat clearing, and occasional dysphagia due to inflammation but have never experienced any hoarseness and was listed as having possible NERD too. Sometimes I wonder if this is really reflux-related at all. I am now trying to wean myself off PPI's again and am terrified.
Feel Good,

-Faith

bcfromfl
Regular Member


Date Joined Nov 2011
Total Posts : 417
   Posted 12/15/2011 2:25 PM (GMT -6)   
Hi Faith --

If you describe yourself as a side-sleeper, does that mean that you aren't sleeping on an incline? It's not going to relieve all your symptoms by a long shot, but it will manage the severity of them. Try to get your head up about 12-14". I use the foam wedges sold in Bed Bath & Beyond, that are long enough to go down to your hips. Utilized in conjunction with meal and diet adjustments, you may find that you can manage OK without the PPIs, although, as I said, you won't eliminate all of the discomfort.

I can not take PPIs because of the massive headaches they cause, but I do everything else, including Gaviscon before bed. The Gaviscon only lasts maybe three hours or so, but it all helps.

-Bruce

Faith224
Regular Member


Date Joined Sep 2011
Total Posts : 299
   Posted 12/15/2011 2:36 PM (GMT -6)   
I actually have a wedge and I find myself waking up in the morning on my side.
Feel Good,

-Faith
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