Sulcrafate and Levothyroxine

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

lozzy42
Regular Member


Date Joined Jul 2011
Total Posts : 106
   Posted 12/24/2011 3:21 AM (GMT -6)   
Hi guys

Just a quick post, I was prescribed Sulcrafate today as my doc said it would help me. What he failed to tell me, was that it can interact with my Thyroxine?? I have read that you need to take it between 4 and 8 hours apart. Has anyone else been on these two drugs as I could really do with some advice?

Thanks in advance, and a Merry Christmas

Loz x

mudmagnetmum
Veteran Member


Date Joined Apr 2011
Total Posts : 1604
   Posted 12/24/2011 8:03 AM (GMT -6)   
http://www.consultantlive.com/endocrine-diseases/content/article/10162/1337777

If you look at the above link it does say that Sucralfate binds levothyroxine, making it unavailable. It cites an older article from 1994.

http://www.allthyroid.org/disorders/treatments/levothyroxine_dose.html

According to the second link, Levothyroxine should be taken on a completely empty stomach to maximise absorption.

I think your best bet is to go and chat to a pharmacist, or ring your local chemist if you can't get there in the next couple of days.

The best thing I can think to do is to take your L-thyroxine very early morning and then have breakfast after it's had chance to get through. Maybe then you could have your first dose of Sucralfate before lunch? This is just a suggestion of course - you do need to get some professional advice on it.

MMM
New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma

mudmagnetmum
Veteran Member


Date Joined Apr 2011
Total Posts : 1604
   Posted 12/24/2011 8:08 AM (GMT -6)   
Also, if you Google "drug interaction checker" and enter the 2 drug names, it comes up with a "severe" interaction warning. It says leaving a gap of one hour between L-thyroxine and Sucralfate may limit the interaction - but not totally. Basically, with some experimentation you might find a way to take it, but you will need someone to monitor your thyroid hormone levels. It may be that the professional medical advice will turn out to be that you shouldn't take the Sucralfate - sorry!

MMM
New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma

dencha
Forum Moderator


Date Joined Feb 2009
Total Posts : 7188
   Posted 12/24/2011 8:29 AM (GMT -6)   
Hi Lozzy,
I don't know a thing about the two drugs interating, although MMM covered that very nicely, adding excellent advice.  I can speak to the Sucrafate.  It will coat your stomach and help it to heal.
 
Even if you took just two doses of Sucrafate it would be helpful.  So, as MMM said, you could take the Levothyroxine (assuming you are only to take it once a day) first thing in the morning, wait the appropriate time, then at the appropriate spaced moment, take the Sucrafate.  You can at least get two, (maybe three if you're only taking Levothyroxine once a day) or even three, with one at bedtime, doses of Sucrafate.
 
Definitely see if a pharmacist can work up a schedule for you.
Good catch!  Your doctor should have discussed this with you.  It was definitely a miss for him/her.
 
Good luck!
Denise

lozzy42
Regular Member


Date Joined Jul 2011
Total Posts : 106
   Posted 12/26/2011 1:02 AM (GMT -6)   
Thanks for the advice guys, unfortunately my doc's aren't very good at spotting stuff like this, that's why I always do a bit of research myself. I have been taking my thyroxine around 6am and taking the first sulcrafate around 12pm so I'm getting a good 6 hours after my thyroxine, I hope that it's enough time to stop the two from interacting??? I have made an appointment for the 11 Jan to see a doc to discuss this with, as I need to be sure that the time I'm leaving is long enough.


Cheers

Loz

mudmagnetmum
Veteran Member


Date Joined Apr 2011
Total Posts : 1604
   Posted 12/26/2011 5:16 AM (GMT -6)   
That's probably a good strategy. I think you may get better answers out of a pharmacist though - also I wondered if there are contact details for the Sucralfate manufacturers, as it's possible they will have their own technical staff who could advise you. Might be worth writing to them to get the info from the top source as it were.

MMM
New stuff: GERD. Interstitial Cystitis
Lifelong stuff: Food allergies, eczema, asthma

lozzy42
Regular Member


Date Joined Jul 2011
Total Posts : 106
   Posted 12/26/2011 7:25 PM (GMT -6)   
That's a great idea, I'll do that cheers!

mudmagnetmum said...
That's probably a good strategy. I think you may get better answers out of a pharmacist though - also I wondered if there are contact details for the Sucralfate manufacturers, as it's possible they will have their own technical staff who could advise you. Might be worth writing to them to get the info from the top source as it were.

MMM
New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, September 18, 2018 9:56 PM (GMT -6)
There are a total of 3,004,492 posts in 329,146 threads.
View Active Threads


Who's Online
This forum has 161740 registered members. Please welcome our newest member, Liz in Colorado.
191 Guest(s), 2 Registered Member(s) are currently online.  Details
CAdogsRus, (Seashell)