I saw a little improvement in the first two weeks, and continued gradual improvement over at least two months and probably longer. The most important thing for me is keeping the fat content of my food quite low. I also balance acidity with alkaline foods: if I have fruit or yogurt, which are both slightly acidic, I also eat a few low-fat crackers or bread. If you are interested in the diet, read my first post on that thread, it includes many important details: https://www.healingwell.com/community/default.aspx?f=45&m=2210975
I started this diet on 80 mg Nexium, went down to 40 mg Nexium after a month, and recently changed to 40 mg Prilosec (which is less powerful). I have also implemented many lifestyle changes, including no eating for 3 hours before bed, and going to sleep in a pretty upright position. I recline after 6 hours have pased since I last ate, that's when all of the food will be out of your stomach.